Literature DB >> 18068462

Anatomic excision of anterior prostatic fat at radical prostatectomy: implications for pathologic upstaging.

David S Finley1, Leslie Deane, Esequiel Rodriguez, John Vallone, Suvarna Deshmukh, Douglas Skarecky, Philip Carpenter, Navneet Narula, David K Ornstein, Thomas E Ahlering.   

Abstract

INTRODUCTION: After exposure of the retropubic space, the surgeon commonly dissects the fat overlying the prostate and usually discards it. We have previously described the importance of dissecting this fat to completely visualize the dorsal venous complex (DVC) and prostatic apex. In this study, we describe a technique to dissect and remove the anterior prostatic fat pad (APF) and its anatomic and pathologic significance. TECHNICAL CONSIDERATIONS: After the retropubic space was prepared, we dissected the fat overlying the puboprostatic ligaments and the DVC to fully expose these structures. The superficial branch of the DVC was then transected, and the fat was dissected cephalad to the junction with the bladder. The fat was then further dissected laterally toward the lateral pelvic sidewall. Video analysis of the lateral dissection of the fat revealed a direct link to the obturator lymph node chain, where it was transected. Pathologic analysis demonstrated that 30 (14.7%) of 204 patients had one or more APF lymph nodes, of which four were positive for metastatic prostate cancer. The cancer of 3 of these 4 patients was upstaged as a result of the detection of these positive nodes.
CONCLUSIONS: The dissection of the APF facilitates visualization of the apex and bladder neck. Anatomically, we have demonstrated that the APF contains lymph nodes approximately 15% of the time that are in communication with the obturator lymph node chain and DVC. We found that removal of the APF and its pathologic analysis can result in pathologic upstaging.

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Year:  2007        PMID: 18068462     DOI: 10.1016/j.urology.2007.09.028

Source DB:  PubMed          Journal:  Urology        ISSN: 0090-4295            Impact factor:   2.649


  9 in total

1.  Role of anterior prostatic fat pad dissection for extended lymphadenectomy in prostate cancer: a non-randomized study of 100 patients.

Authors:  Burak Ozkan; Burcin Tunc; Enis Rauf Coskuner; Yesim Saglican; Veli Yalçın
Journal:  Int Urol Nephrol       Date:  2015-04-22       Impact factor: 2.370

2.  Robotic-assisted laparoscopic radical prostatectomy after aborted retropubic radical prostatectomy.

Authors:  Keith J Kowalczyk; Andy C Huang; Stephen B Williams; Hua-Yin Yu; Jim C Hu
Journal:  J Robot Surg       Date:  2012-08-19

3.  Can Anterior Prostatic Fat Harbor Prostate Cancer Metastasis? A Prospective Cohort Study.

Authors:  Mohannad Hosny; Bhavan Rai; Feras Aljaafari; Samita Agarwal; Thomas McNicholas; Gregory Boustead; Thimothy Lane; James Adshead; Nikhil Vasdev
Journal:  Curr Urol       Date:  2017-10-22

4.  Pre-prostatic tissue removed in robotic assisted lymph node dissection for prostate cancer contains lymph nodes.

Authors:  J Blarer; C Padevit; K Horton; D Pfofe; H John; M Horstmann
Journal:  Urol Ann       Date:  2013-10

5.  Does prostate acinar adenocarcinoma with Gleason Score 3+3=6 have the potential to metastasize?

Authors:  Rodolfo Montironi; Marina Scarpelli; Roberta Mazzucchelli; Antonio Lopez-Beltran; Matteo Santoni; Alberto Briganti; Francesco Montorsi; Liang Cheng
Journal:  Diagn Pathol       Date:  2014-10-18       Impact factor: 2.644

6.  Does anterior prostatic fat tissue removed during robotic radical prostatectomy contain any lymph nodes?

Authors:  Ali Fuat Atmaca; Abdullah Erdem Canda; Murat Keske; Muhammed Ersagun Arslan; Davut Kamaci; Erdal Alkan; Mevlana Derya Balbay
Journal:  Cent European J Urol       Date:  2015-12-21

7.  Robotic-assisted radical prostatectomy after the first decade: surgical evolution or new paradigm.

Authors:  Douglas W Skarecky
Journal:  ISRN Urol       Date:  2013-04-03

8.  Oncologic outcomes in men with metastasis to the prostatic anterior fat pad lymph nodes: a multi-institution international study.

Authors:  Young Suk Kwon; Yun-Sok Ha; Parth K Modi; Amirali Salmasi; Jaspreet S Parihar; Neal Patel; Izak Faiena; Michael May; David I Lee; Elton Llukani; Tuliao Patrick; Koon Ho Rha; Thomas Ahlering; Douglas Skarecky; Hanjong Ahn; Seung-Kwon Choi; Sejun Park; Seong Soo Jeon; Yen-Chuan Ou; Daniel Eun; Varsha Manucha; David Albala; Ketan Badani; Bertram Yuh; Nora Ruel; Tae-Hwan Kim; Tae Gyun Kwon; Daniel Marchalik; Jonathan Hwang; Wun-Jae Kim; Isaac Yi Kim
Journal:  BMC Urol       Date:  2015-08-01       Impact factor: 2.264

9.  Impact of prostatic anterior fat pads with lymph node staging in prostate cancer.

Authors:  Wei-Chun Weng; Li-Hua Huang; Chao-Yu Hsu; Min-Che Tung; Cheng-Kuang Yang; Jong-Shiaw Jin; Yen-Chuan Ou; Shun-Fa Yang
Journal:  J Cancer       Date:  2018-09-08       Impact factor: 4.207

  9 in total

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