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Literature DB >> 18067932

Polyketides from Penicillium sp. JP-1, an endophytic fungus associated with the mangrove plant Aegiceras corniculatum.

Zhenjian Lin¹, Tianjiao Zhu, Yuchun Fang, Qianqun Gu, Weiming Zhu.

Abstract

Four polyketides, leptosphaerone C (1), penicillenone (2), arugosin I (3) and 9-demethyl FR-901235 (4), as well as five known compounds, bacillosporin A (5), bacillosporin C (6), sequoiamonascin D (7), sequoiatone A (8), and sequoiatone B (9) were isolated from the Penicillium sp. JP-1, an endophytic fungus isolated from Aegiceras corniculatum. Their structures were determined by spectroscopic methods, mainly by 2D NMR spectroscopic analyses. Compound 1 showed cytotoxicity against A-549 cells with an IC50 value of 1.45 microM, while compound 2 showed cytotoxicity against P388 cells with an IC50 value of 1.38 microM.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 2007 PMID： 18067932 DOI： 10.1016/j.phytochem.2007.10.030

Source DB: PubMed Journal: Phytochemistry ISSN： 0031-9422 Impact factor: 4.072

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Cited

18 in total

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Journal: Mar Biotechnol (NY) Date: 2014-08-10 Impact factor: 3.619

Review 2. Endophytic Penicillium species and their agricultural, biotechnological, and pharmaceutical applications.

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Journal: 3 Biotech Date: 2020-02-08 Impact factor: 2.406

3. Genetic, molecular, and biochemical basis of fungal tropolone biosynthesis.

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Journal: Proc Natl Acad Sci U S A Date: 2012-04-16 Impact factor: 11.205

4. Endophytic fungi diversity of aquatic/riparian plants and their antifungal activity in vitro.

Authors: Hai-Yan Li; Chun-An Zhao; Chen-Jian Liu; Xiao-Fei Xu
Journal: J Microbiol Date: 2010-03-11 Impact factor: 3.422

5. Identification of Hortaea werneckii Isolated from mangrove plant Aegiceras comiculatum based on morphology and rDNA sequences.

Authors: Juan Chen; Xiao-Ke Xing; Li-Chun Zhang; Yong-Mei Xing; Shun-Xing Guo
Journal: Mycopathologia Date: 2012-08-03 Impact factor: 2.574

Polyketides from Penicillium sp. JP-1, an endophytic fungus associated with the mangrove plant Aegiceras corniculatum.

1. Acetylcholinesterase inhibitors from a marine fungus Talaromyces sp. strain LF458.

Review 2. Endophytic Penicillium species and their agricultural, biotechnological, and pharmaceutical applications.

3. Genetic, molecular, and biochemical basis of fungal tropolone biosynthesis.

4. Endophytic fungi diversity of aquatic/riparian plants and their antifungal activity in vitro.

5. Identification of Hortaea werneckii Isolated from mangrove plant Aegiceras comiculatum based on morphology and rDNA sequences.

Review 6. Cure lies in nature: medicinal plants and endophytic fungi in curbing cancer.

Review 7. Secondary Metabolites of Mangrove-Associated Strains of Talaromyces.

8. A set of interesting sequoiatones stereoisomers from a wetland soil-derived fungus Talaromyces flavus.

9. Polyketides From the Endophytic Fungus Cladosporium sp. Isolated From the Mangrove Plant Excoecaria agallocha.

10. Tyrosinase Inhibitors from the Stems of Streblus Ilicifolius.