Hai-hong Zhu1, Han-liang Jiang, Zhi Chen. 1. Institute of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China.
Abstract
OBJECTIVE: To develop a high-throughput diagnostic method with suspension array technique for detecting pathogenic microbes. METHODS: The probes and positive controls of 56 kinds of pathogenic microbes were designed, synthesized, and used to detect pathogenic microbes with suspension array technique. RESULTS: Fluorescence signals of 56 positive controls were higher than those of the negative controls, and there was no cross-reaction between the probes and positive controls of different microbes. CONCLUSION: Based on suspension array technique, the high-throughput diagnostic method may be useful in clinical detection of pathogenic microbes.
OBJECTIVE: To develop a high-throughput diagnostic method with suspension array technique for detecting pathogenic microbes. METHODS: The probes and positive controls of 56 kinds of pathogenic microbes were designed, synthesized, and used to detect pathogenic microbes with suspension array technique. RESULTS: Fluorescence signals of 56 positive controls were higher than those of the negative controls, and there was no cross-reaction between the probes and positive controls of different microbes. CONCLUSION: Based on suspension array technique, the high-throughput diagnostic method may be useful in clinical detection of pathogenic microbes.