Literature DB >> 18066799

Synthesis of 1'-C-fluoromethyladenosine.

Annelaure Damont1, David Dukhan, Gilles Gosselin, Jérôme Peyronnet, Richard Storer.   

Abstract

In search for new antiviral agents, we have been interested in 1'-C-fluoromethyl branched ribonucleosides. In this paper, we describe the synthesis of 1'-C-fluoromethyladenosine via electrophilic fluorination of exo-glycal.

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Year:  2007        PMID： 18066799     DOI： 10.1080/15257770701542165

Source DB:  PubMed          Journal:  Nucleosides Nucleotides Nucleic Acids        ISSN： 1525-7770            Impact factor:   1.381


  2 in total

Review 1.  The evolution of antiviral nucleoside analogues: A review for chemists and non-chemists. Part II: Complex modifications to the nucleoside scaffold.

Authors:  Mary K Yates; Katherine L Seley-Radtke
Journal:  Antiviral Res       Date:  2018-12-08       Impact factor: 10.103

2.  Synthesis and antiviral activity of a series of 1'-substituted 4-aza-7,9-dideazaadenosine C-nucleosides.

Authors:  Aesop Cho; Oliver L Saunders; Thomas Butler; Lijun Zhang; Jie Xu; Jennifer E Vela; Joy Y Feng; Adrian S Ray; Choung U Kim
Journal:  Bioorg Med Chem Lett       Date:  2012-03-08       Impact factor: 2.823
  2 in total

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