[Somatoform disorders. Clinical evidence, etiology, pathogenesis, and therapy].

Patients presenting with bodily symptoms and complaints that are not explained by organic pathology or well-known pathophysiological mechanisms comprise a major challenge to any medical care system. From a perspective of psychiatric classification, such medically unexplained somatic symptoms are diagnosed as depressive and anxiety disorders on the one hand or somatoform disorders on the other. In clinical physical medicine a quite different diagnostic approach is taken to conceptualize functional somatic syndromes. Concepts of somatoform disorders are outlined, critical issues regarding existing diagnostic systems are discussed, and possible alternative approaches for upcoming versions of DSM-V and ICD-11 are mentioned. The main somatoform disorders are described in their clinical characteristics. Etiopathogenetically, somatoform disorders may best be considered within a multifactorial model. Some pragmatic guidelines for multimodal treatment of somatoform disorders are outlined.