Literature DB >> 18066507

[Metabolic alkalosis despite hyperlactatemia and hypercapnia. Interpretation and therapy with help of the Stewart concept].

D Chappell1, K Hofmann-Kiefer, M Jacob, P Conzen, M Rehm.   

Abstract

Acid-base disturbances are commonly found in critically ill patients and are often associated with fatal complications. The basis of a successful treatment is a thorough understanding of the causes of these disorders. The "classical methods" to explain acid-base disorders--pH, base excess and bicarbonate concentration--mostly do not provide a causal correlation to the underlying pathology. An unusual case of a combined respiratory-metabolic disorder with hyperlactatemia and hypercapnia is presented. An acidosis masked by hypochloremic and hypoalbuminemic alkalosis was identified with the help of Stewart's concept and finally permitted a successful therapy. The modern Stewart concept provides enhanced information, enabling an exact diagnosis and causal therapy even in complex cases.

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Year:  2008        PMID: 18066507     DOI: 10.1007/s00101-007-1288-4

Source DB:  PubMed          Journal:  Anaesthesist        ISSN: 0003-2417            Impact factor:   1.041


  14 in total

1.  Serum proteins and acid-base equilibria: a follow-up.

Authors:  J Figge; T Mydosh; V Fencl
Journal:  J Lab Clin Med       Date:  1992-11

2.  The acid-base status of the blood.

Authors:  O SIGGAARD-ANDERSEN
Journal:  Scand J Clin Lab Invest       Date:  1963       Impact factor: 1.713

3.  The acid-base metabolism. A new approach.

Authors:  P ASTRUP; K JORGENSEN; O S ANDERSEN; K ENGEL
Journal:  Lancet       Date:  1960-05-14       Impact factor: 79.321

4.  Diagnosis of metabolic acid-base disturbances in critically ill patients.

Authors:  V Fencl; A Jabor; A Kazda; J Figge
Journal:  Am J Respir Crit Care Med       Date:  2000-12       Impact factor: 21.405

5.  Comparison of three different methods of evaluation of metabolic acid-base disorders.

Authors:  Arnaldo Dubin; María M Menises; Fabio D Masevicius; Miriam C Moseinco; Daniela Olmos Kutscherauer; Elizabeth Ventrice; Enrique Laffaire; Elisa Estenssoro
Journal:  Crit Care Med       Date:  2007-05       Impact factor: 7.598

6.  Modern quantitative acid-base chemistry.

Authors:  P A Stewart
Journal:  Can J Physiol Pharmacol       Date:  1983-12       Impact factor: 2.273

Review 7.  [The Stewart model. "Modern" approach to the interpretation of the acid-base metabolism].

Authors:  M Rehm; P F Conzen; K Peter; U Finsterer
Journal:  Anaesthesist       Date:  2004-04       Impact factor: 1.041

8.  Alkalemia-associated morbidity and mortality in medical and surgical patients.

Authors:  L E Anderson; W L Henrich
Journal:  South Med J       Date:  1987-06       Impact factor: 0.954

9.  Cardiovascular performance and oxyhemoglobin dissociation after acetazolamide in metabolic alkalosis.

Authors:  P Berthelsen
Journal:  Intensive Care Med       Date:  1982       Impact factor: 17.440

10.  Incidence of metabolic alkalemia in hospitalized patients.

Authors:  J E Hodgkin; F F Soeprono; D M Chan
Journal:  Crit Care Med       Date:  1980-12       Impact factor: 7.598

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  4 in total

1.  [Acid-base concepts].

Authors:  W Lang; M Rehm
Journal:  Anaesthesist       Date:  2009-03       Impact factor: 1.041

2.  [Acid-base analytic: A never ending story].

Authors:  Rolf Zander
Journal:  Anaesthesist       Date:  2008-08       Impact factor: 1.041

Review 3.  Effect of Intravenously Administered Crystalloid Solutions on Acid-Base Balance in Domestic Animals.

Authors:  W Muir
Journal:  J Vet Intern Med       Date:  2017-08-20       Impact factor: 3.333

4.  Severe hyperlactatemia with normal base excess: a quantitative analysis using conventional and Stewart approaches.

Authors:  Graciela Tuhay; María Carolina Pein; Fabio Daniel Masevicius; Daniela Olmos Kutscherauer; Arnaldo Dubin
Journal:  Crit Care       Date:  2008-05-08       Impact factor: 9.097

  4 in total

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