Literature DB >> 18062906

The Mx GTPase family of interferon-induced antiviral proteins.

Otto Haller1, Silke Stertz, Georg Kochs.   

Abstract

Mx proteins are interferon-induced members of the dynamin superfamily of large GTPases. They inhibit a wide range of viruses by blocking an early stage of the replication cycle. Studies in genetically defined mouse strains highlight their powerful action in early antiviral host defence.

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Year:  2007        PMID: 18062906     DOI: 10.1016/j.micinf.2007.09.010

Source DB:  PubMed          Journal:  Microbes Infect        ISSN: 1286-4579            Impact factor:   2.700


  73 in total

1.  Glycine 184 in nonstructural protein NS1 determines the virulence of influenza A virus strain PR8 without affecting the host interferon response.

Authors:  Sabine Steidle; Luis Martínez-Sobrido; Markus Mordstein; Stefan Lienenklaus; Adolfo García-Sastre; Peter Stäheli; Georg Kochs
Journal:  J Virol       Date:  2010-10-06       Impact factor: 5.103

2.  Mx is dispensable for interferon-mediated resistance of chicken cells against influenza A virus.

Authors:  Benjamin Schusser; Antje Reuter; Alexander von der Malsburg; Nicola Penski; Steffen Weigend; Bernd Kaspers; Peter Staeheli; Sonja Härtle
Journal:  J Virol       Date:  2011-06-01       Impact factor: 5.103

Review 3.  Dynamin-like MxA GTPase: structural insights into oligomerization and implications for antiviral activity.

Authors:  Otto Haller; Song Gao; Alexander von der Malsburg; Oliver Daumke; Georg Kochs
Journal:  J Biol Chem       Date:  2010-06-10       Impact factor: 5.157

4.  Chromatin dynamics of gene activation and repression in response to interferon alpha (IFN(alpha)) reveal new roles for phosphorylated and unphosphorylated forms of the transcription factor STAT2.

Authors:  Barbara Testoni; Christine Völlenkle; Francesca Guerrieri; Sabine Gerbal-Chaloin; Giovanni Blandino; Massimo Levrero
Journal:  J Biol Chem       Date:  2011-04-15       Impact factor: 5.157

5.  Association of multi-pathogenic infections with BAT2, CXCL12, Mx1 and EHMT2 variations in pigs.

Authors:  S J Wang; W J Liu; L G Yang; H B Liu; C A Sargent; N A Affara; S J Zhang
Journal:  Mol Biol Rep       Date:  2012-04-25       Impact factor: 2.316

6.  Dynamins at a glance.

Authors:  Jürgen A W Heymann; Jenny E Hinshaw
Journal:  J Cell Sci       Date:  2009-10-01       Impact factor: 5.285

7.  Functional characterization of canine interferon-lambda.

Authors:  Wenhui Fan; Lei Xu; Liqian Ren; Hongren Qu; Jing Li; Jingjing Liang; Wenjun Liu; Limin Yang; Tingrong Luo
Journal:  J Interferon Cytokine Res       Date:  2014-06-20       Impact factor: 2.607

8.  Inhibition of tumor cell motility by the interferon-inducible GTPase MxA.

Authors:  J Frederic Mushinski; Phuongmai Nguyen; Lisa M Stevens; Chand Khanna; Sunmin Lee; Eun Joo Chung; Min-Jung Lee; Yeong Sang Kim; W Marston Linehan; Michel A Horisberger; Jane B Trepel
Journal:  J Biol Chem       Date:  2009-03-18       Impact factor: 5.157

9.  Genotype frequency contributions of Mx1 gene in eight chicken breeds under different selection pressures.

Authors:  Jingjing Li; Chaowu Yang; Jinshan Ran; Xiaosong Jiang; Huarui Du; Zhiqiang Li; Yiping Liu; Long Zhang
Journal:  3 Biotech       Date:  2018-11-14       Impact factor: 2.406

10.  Murine guanylate binding protein 2 (mGBP2) controls Toxoplasma gondii replication.

Authors:  Daniel Degrandi; Elisabeth Kravets; Carolin Konermann; Cornelia Beuter-Gunia; Verena Klümpers; Sarah Lahme; Eva Rasch; Anne K Mausberg; Sandra Beer-Hammer; Klaus Pfeffer
Journal:  Proc Natl Acad Sci U S A       Date:  2012-12-17       Impact factor: 11.205

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