Literature DB >> 18062673

Formation of substituted pyrroles via an imine condensation/Aza-Claisen rearrangement/imine-allene cyclization process by MAOS.

W Stacy Bremner1, Michael G Organ.   

Abstract

A diverse collection of pyrroles has been prepared using a one-pot, domino aldehyde/amine condensation, [3,3]-aza-Claisen rearrangement, imine-allene cyclization strategy. This protocol was accelerated by microwave irradiation and provided very good levels of conversion after reacting for only 30 min.

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Year:  2007        PMID: 18062673     DOI: 10.1021/cc700159u

Source DB:  PubMed          Journal:  J Comb Chem        ISSN: 1520-4766


  2 in total

Review 1.  Controlled microwave heating in modern organic synthesis: highlights from the 2004-2008 literature.

Authors:  C Oliver Kappe; Doris Dallinger
Journal:  Mol Divers       Date:  2009-04-21       Impact factor: 2.943

Review 2.  Benefits and applications of microwave-assisted synthesis of nitrogen containing heterocycles in medicinal chemistry.

Authors:  Maged Henary; Carl Kananda; Laura Rotolo; Brian Savino; Eric A Owens; Giancarlo Cravotto
Journal:  RSC Adv       Date:  2020-04-07       Impact factor: 3.361

  2 in total

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