Literature DB >> 18062521

Hystroscopic management of Ashermans syndrome.

Haleema Yasmin1, Ayesha Nasir, Khurshid J Noorani.   

Abstract

OBJECTIVE: To confirm the diagnosis of Asherman's syndrome in patients with scanty menses/amenorrhoea or infertility and to assess the effectiveness of hysteroscopy in the treatment of Asherman's syndrome.
METHODS: A hospital based descriptive study conducted on 20 patients presenting with amenorrhoea, oligomenorrhoea, or infertility from Jan 2004 to June 2005. They were selected after excluding hormonal imbalances, premature ovarian failure and congenital uterine abnormalities. All patients underwent diagnostic hysteroscopy and resection of adhesions. Specimens were sent for Histopathology and bacterial culture. RESULT: A total of 20 patients were included in this study, the median age was 26 years, 65% had presented with scanty menses with secondary infertility, 20% with secondary ammenorrhoea, and 15% with primary infertility alone. Hysteroscopic findings showed thick fibrous adhesions in 45% patients, 40% had flimsy adhesions and 15% had muscular adhesions. It was seen that 65% had adhesions in the body of uterus, 25% at the site of internal os and 1% had adhesions in the cervical canal as well as the body of the uterus. Normal menstrual cycle was resumed in 95% patients, whereas two patients conceived and were followed to term. Dense fibrous tissue with few patches of calcification and no signs of secretory or proliferative cells was found in 35% patients. In 45% endometrium showed proliferative changes and collagen fibers. Only 1 patient had a positive AFB culture and the histopathology showed few graulomas with epitheloid cells most of the tissue replaced by necrotic tissue with patchy areas of caseation.
CONCLUSION: Hysteroscopy is an effective procedure for not only diagnosing Ashermans Syndrome, but is equally effective for treating it..

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Year:  2007        PMID: 18062521

Source DB:  PubMed          Journal:  J Pak Med Assoc        ISSN: 0030-9982            Impact factor:   0.781


  8 in total

1.  Hysteroscopic adhesiolysis for patients with Asherman's syndrome: menstrual and fertility outcomes.

Authors:  Nari Yamamoto; Reiko Takeuchi; Daisuke Izuchi; Norihito Yuge; Masahide Miyazaki; Masafumi Yasunaga; Katsuko Egashira; Yousuke Ueoka; Yoshihito Inoue
Journal:  Reprod Med Biol       Date:  2013-05-05

2.  Experience with Hysteroscopy in a Private Specialist Hospital in Nigeria.

Authors:  James A Osaikhuwuomwan; Israel Ikekwuibe; Michael E Aziken
Journal:  Niger Med J       Date:  2020-07-04

Review 3.  Efficacy of intrauterine device in the treatment of intrauterine adhesions.

Authors:  Umme Salma; Min Xue; Ali Sheikh Md Sayed; Dabao Xu
Journal:  Biomed Res Int       Date:  2014-09-01       Impact factor: 3.411

4.  A 10-year Review of the Clinical Presentation and Treatment Outcome of Asherman's Syndrome at a Center with Limited Resources.

Authors:  I U Takai; A S Kwayabura; E A Ugwa; A Idrissa; J Y Obed; M Bukar
Journal:  Ann Med Health Sci Res       Date:  2015 Nov-Dec

5.  The role of G-CSF in recurrent implantation failure: A randomized double blind placebo control trial.

Authors:  Fatemeh Davari-Tanha; Ensieh Shahrokh Tehraninejad; Mohadese Ghazi; Zahra Shahraki
Journal:  Int J Reprod Biomed (Yazd)       Date:  2016-12

6.  AAGL practice report: practice guidelines on intrauterine adhesions developed in collaboration with the European Society of Gynaecological Endoscopy (ESGE).

Authors: 
Journal:  Gynecol Surg       Date:  2017-05-01

7.  Single cell-derived clonally expanded mesenchymal progenitor cells from somatic cell nuclear transfer-derived pluripotent stem cells ameliorate the endometrial function in the uterus of a murine model with Asherman's syndrome.

Authors:  Sung-Min Jun; Mira Park; Ji Yoon Lee; Sookyung Jung; Jeoung Eun Lee; Sung Han Shim; Haengseok Song; Dong Ryul Lee
Journal:  Cell Prolif       Date:  2019-03-21       Impact factor: 6.831

8.  Reproductive Outcome of Patients with Asherman's Syndrome: A SAIMS Experience.

Authors:  Shilpa Bhandari; Priya Bhave; Ishita Ganguly; Asha Baxi; Pallavi Agarwal
Journal:  J Reprod Infertil       Date:  2015 Oct-Dec
  8 in total

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