Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Medicinal chemistry aspects of drug targets in sphingolipid metabolism.

× No keyword cloud information.

8 in total

1. Novel synthesis and biological evaluation of enigmols as therapeutic agents for treating prostate cancer.

Authors: Ethel C Garnier-Amblard; Suzanne G Mays; Richard F Arrendale; Mark T Baillie; Anatoliy S Bushnev; Deborah G Culver; Taylor J Evers; Jason J Holt; Randy B Howard; Lanny S Liebeskind; David S Menaldino; Michael G Natchus; John A Petros; Harsha Ramaraju; G Prabhakar Reddy; Dennis C Liotta
Journal: ACS Med Chem Lett Date: 2011-03-25 Impact factor: 4.345

2. Sphingosine 1-phosphate lyase inhibition by 2-acetyl-4-(tetrahydroxybutyl)imidazole (THI) under conditions of vitamin B6 deficiency.

Authors: Mamoru Ohtoyo; Masakazu Tamura; Nobuo Machinaga; Fumihito Muro; Ryuji Hashimoto
Journal: Mol Cell Biochem Date: 2014-11-09 Impact factor: 3.396

3. Ceramides: branched alkyl chains in the sphingolipid siblings of diacylglycerol improve biological potency.

Authors: Ji-Hye Kang; Himanshu Garg; Dina M Sigano; Nicholas Francella; Robert Blumenthal; Victor E Marquez
Journal: Bioorg Med Chem Date: 2009-01-11 Impact factor: 3.641

4. Improved synthesis of a fluorogenic ceramidase substrate.

Authors: Zuping Xia; Jeremiah M Draper; Charles D Smith
Journal: Bioorg Med Chem Date: 2010-01-06 Impact factor: 3.641

Review 5. Sphingosine 1-phosphate lyase, a key regulator of sphingosine 1-phosphate signaling and function.

Authors: Montserrat Serra; Julie D Saba
Journal: Adv Enzyme Regul Date: 2009-11-13

6. Benzoxazolone carboxamides: potent and systemically active inhibitors of intracellular acid ceramidase.

Authors: Daniela Pizzirani; Anders Bach; Natalia Realini; Andrea Armirotti; Luisa Mengatto; Inga Bauer; Stefania Girotto; Chiara Pagliuca; Marco De Vivo; Maria Summa; Alison Ribeiro; Daniele Piomelli
Journal: Angew Chem Int Ed Engl Date: 2014-11-13 Impact factor: 15.336

7. Fragment-Based Hologram QSAR Studies on a Series of 2,4-Dioxopyrimidine-1-Carboxamides As Highly Potent Inhibitors of Acid Ceramidase.

Authors: Xiang-Lin Yang; Yuan Zhou; Xin-Ling Liu
Journal: Iran J Pharm Res Date: 2016 Impact factor: 1.696

8. Synthesis and characterization of long-chain tartaric acid diamides as novel ceramide-like compounds.

Authors: Bálint Sinkó; Melinda Pálfi; Szabolcs Béni; József Kökösi; Krisztina Takács-Novák
Journal: Molecules Date: 2010-02-05 Impact factor: 4.411

8 in total