| Literature DB >> 1806092 |
L J Allen1, M A Jones, C F Martin.
Abstract
A discrete-time, age-independent SIR-type epidemic model is formulated and analyzed. The effects of vaccination are also included in the model. Three mathematically important properties are verified for the model: solutions are nonnegative, the population size is time-invariant, and the epidemic concludes with all individuals either remaining susceptible or becoming immune (a property typical of SIR models). The model is applied to a measles epidemic on a university campus. The simulated results are in good agreement with the actual data if it is assumed that the population mixes nonhomogeneously. The results of the simulations indicate that a rate of immunity greater than 98% may be required to prevent an epidemic in a university population. The model has applications to other contagious diseases of SIR type. Furthermore, the simulated results of the model can easily be compared to data, and the effects of a vaccination program can be examined.Mesh:
Substances:
Year: 1991 PMID: 1806092 DOI: 10.1016/0025-5564(91)90051-j
Source DB: PubMed Journal: Math Biosci ISSN: 0025-5564 Impact factor: 2.144