Literature DB >> 180596

Ethanol-induced depletion of cerebellar guanosine 3',5' -cyclic monophosphate.

J D Redos, G N Catravas, W A Hunt.   

Abstract

Single doses of ethanol a severe depletion (95 percent) of cerebellar guanosine 3',5' -cyclic monophosphate (cyclic GMP) within 1 hour after administration. The degree of this depletion is dose-dependent and is a function of the amount of ethanol in the blood. Interactions between ethanol and cyclic GMP may account for some of the intoxicating properties of ethanol.

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Year:  1976        PMID: 180596     DOI: 10.1126/science.180596

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  6 in total

1.  Acute and chronic ethanol administration on specific 3H-GABA binding in different rat brain areas.

Authors:  A Reggiani; M L Barbaccia; P F Spano; M Trabucchi
Journal:  Psychopharmacology (Berl)       Date:  1980       Impact factor: 4.530

2.  Immunocytochemical localization of cyclic GMP: light and electron microscope evidence for involvement of neuroglia.

Authors:  V Chan-Palay; S L Palay
Journal:  Proc Natl Acad Sci U S A       Date:  1979-03       Impact factor: 11.205

3.  Characterization and subcellular distribution of specific thyrotropin-releasing hormone binding sites in rat cerebellum.

Authors:  C Prasad; R M Edwards
Journal:  Neurochem Res       Date:  1984-04       Impact factor: 3.996

Review 4.  Thyrotropin-releasing hormone (TRH) in the cerebellum.

Authors:  Nobuyuki Shibusawa; Koshi Hashimoto; Masanobu Yamada
Journal:  Cerebellum       Date:  2008       Impact factor: 3.847

5.  Effects of ethanol and imidazobenzodiazepine Ro 15-4513 on spontaneous saccades of the pigmented rat.

Authors:  F Rossi; L Chelazzi; F Tempia; P Strata
Journal:  Exp Brain Res       Date:  1989       Impact factor: 1.972

6.  The effects of alcohol on cyclic AMP in mouse brain.

Authors:  E K Orenberg; J Renson; J D Barchas
Journal:  Neurochem Res       Date:  1976-12       Impact factor: 3.996

  6 in total

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