| Literature DB >> 18059058 |
Tomofumi Santa1, Takeshi Fukushima, Tomoko Ichibangase, Kazuhiro Imai.
Abstract
Chemical derivatization is often used to enhance the detectability of the target compounds and to improve the separation efficiency in high-performance liquid chromatography (HPLC). In this review, we describe the recent progress in the development of derivatization reagents having a benzofurazan structure, namely, the fluorogenic reagents, water-soluble reagents, reagents for the analysis of peptides and proteins, and reagents for mass spectrometric detection. The application of these reagents to bio-samples is also briefly described.Entities:
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Year: 2008 PMID: 18059058 DOI: 10.1002/bmc.945
Source DB: PubMed Journal: Biomed Chromatogr ISSN: 0269-3879 Impact factor: 1.902