Literature DB >> 18058781

ESI-MS studies on prolyl hydroxylase domain 2 reveal a new metal binding site.

Jasmin Mecinović1, Rasheduzzaman Chowdhury, Benoît M R Liénard, Emily Flashman, Matthew R G Buck, Neil J Oldham, Christopher J Schofield.   

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Year:  2008        PMID： 18058781     DOI： 10.1002/cmdc.200700233

Source DB:  PubMed          Journal:  ChemMedChem        ISSN： 1860-7179            Impact factor:   3.466


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  12 in total

1.  Distinct deregulation of the hypoxia inducible factor by PHD2 mutants identified in germline DNA of patients with polycythemia.

Authors:  Charline Ladroue; David Hoogewijs; Sophie Gad; Romain Carcenac; Federica Storti; Michel Barrois; Anne-Paule Gimenez-Roqueplo; Michel Leporrier; Nicole Casadevall; Olivier Hermine; Jean-Jacques Kiladjian; André Baruchel; Fadi Fakhoury; Brigitte Bressac-de Paillerets; Jean Feunteun; Nathalie Mazure; Jacques Pouysségur; Roland H Wenger; Stéphane Richard; Betty Gardie
Journal:  Haematologica       Date:  2011-09-20       Impact factor: 9.941

2.  Vitamin C is dispensable for oxygen sensing in vivo.

Authors:  Katarzyna J Nytko; Nobuyo Maeda; Philipp Schläfli; Patrick Spielmann; Roland H Wenger; Daniel P Stiehl
Journal:  Blood       Date:  2011-02-23       Impact factor: 22.113

3.  Affinity-Based Fluorescence Polarization Assay for High-Throughput Screening of Prolyl Hydroxylase 2 Inhibitors.

Authors:  Yonghua Lei; Tianhan Hu; Xingsen Wu; Yue Wu; Qichao Bao; Lianshan Zhang; Hua Xia; Haopeng Sun; Qidong You; Xiaojin Zhang
Journal:  ACS Med Chem Lett       Date:  2015-11-09       Impact factor: 4.345

Review 4.  HIF1, HSF1, and NRF2: Oxidant-Responsive Trio Raising Cellular Defenses and Engaging Immune System.

Authors:  Anna M Cyran; Anatoly Zhitkovich
Journal:  Chem Res Toxicol       Date:  2022-08-10       Impact factor: 3.973

5.  Reporter ligand NMR screening method for 2-oxoglutarate oxygenase inhibitors.

Authors:  Ivanhoe K H Leung; Marina Demetriades; Adam P Hardy; Clarisse Lejeune; Tristan J Smart; Andrea Szöllössi; Akane Kawamura; Christopher J Schofield; Timothy D W Claridge
Journal:  J Med Chem       Date:  2013-01-04       Impact factor: 7.446

Review 6.  The role of PHD2 mutations in the pathogenesis of erythrocytosis.

Authors:  Betty Gardie; Melanie J Percy; David Hoogewijs; Rasheduzzaman Chowdhury; Celeste Bento; Patrick R Arsenault; Stéphane Richard; Helena Almeida; Joanne Ewing; Frédéric Lambert; Mary Frances McMullin; Christopher J Schofield; Frank S Lee
Journal:  Hypoxia (Auckl)       Date:  2014-07-01

7.  Protective effect of zinc preconditioning against renal ischemia reperfusion injury is dose dependent.

Authors:  Kenny Rao; Kapil Sethi; Joseph Ischia; Luke Gibson; Laurence Galea; Lin Xiao; Mildred Yim; Mike Chang; Nathan Papa; Damien Bolton; Arthur Shulkes; Graham S Baldwin; Oneel Patel
Journal:  PLoS One       Date:  2017-07-07       Impact factor: 3.240

8.  2-Oxoglutarate regulates binding of hydroxylated hypoxia-inducible factor to prolyl hydroxylase domain 2.

Authors:  Martine I Abboud; Tom E McAllister; Ivanhoe K H Leung; Rasheduzzaman Chowdhury; Christian Jorgensen; Carmen Domene; Jasmin Mecinović; Kerstin Lippl; Rebecca L Hancock; Richard J Hopkinson; Akane Kawamura; Timothy D W Claridge; Christopher J Schofield
Journal:  Chem Commun (Camb)       Date:  2018-03-09       Impact factor: 6.222

9.  Selective inhibitors of the JMJD2 histone demethylases: combined nondenaturing mass spectrometric screening and crystallographic approaches.

Authors:  Nathan R Rose; Esther C Y Woon; Guy L Kingham; Oliver N F King; Jasmin Mecinović; Ian J Clifton; Stanley S Ng; Jobina Talib-Hardy; Udo Oppermann; Michael A McDonough; Christopher J Schofield
Journal:  J Med Chem       Date:  2010-02-25       Impact factor: 7.446

10.  Dual-action inhibitors of HIF prolyl hydroxylases that induce binding of a second iron ion.

Authors:  Kar Kheng Yeoh; Mun Chiang Chan; Armin Thalhammer; Marina Demetriades; Rasheduzzaman Chowdhury; Ya-Min Tian; Ineke Stolze; Luke A McNeill; Myung Kyu Lee; Esther C Y Woon; Mukram M Mackeen; Akane Kawamura; Peter J Ratcliffe; Jasmin Mecinović; Christopher J Schofield
Journal:  Org Biomol Chem       Date:  2012-11-15       Impact factor: 3.876
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