Diastereoselective synthesis of 2',3'-dideoxy-beta-C-glucopyranosides as intermediates for the synthesis of 2',3'-dideoxy-beta-D-glucopyranosyl-C-nucleosides.

An extension of the Vorbrüggen method of nucleotide synthesis for the synthesis of C-glucopyranosides, as intermediates for C-nucleosides, is described. It could be shown that the diastereoselectivity of the reaction can be tuned by a simple change of protecting groups.