Literature DB >> 18058099

TLR2 in murine atherosclerosis.

Peter S Tobias1, Linda K Curtiss.   

Abstract

Atherosclerosis was once thought to be solely a disease of lipid accumulation in the vessel wall. It does involve lipid accumulation, but inflammation appears to be an important driving factor. Consequently, our laboratory undertook to examine the role(s) of TLRs, and especially TLR2, in murine models of atherosclerosis.

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Year:  2007        PMID: 18058099     DOI: 10.1007/s00281-007-0102-3

Source DB:  PubMed          Journal:  Semin Immunopathol        ISSN: 1863-2297            Impact factor:   9.623


  45 in total

1.  Delivery of Chlamydia pneumoniae to the vessel wall aggravates atherosclerosis in LDLr-/- mice.

Authors:  A D Hauer; P de Vos; N Peterse; H ten Cate; Th J C van Berkel; F R M Stassen; J Kuiper
Journal:  Cardiovasc Res       Date:  2005-08-19       Impact factor: 10.787

Review 2.  Anti-inflammatory effects of statins: clinical evidence and basic mechanisms.

Authors:  Mukesh K Jain; Paul M Ridker
Journal:  Nat Rev Drug Discov       Date:  2005-12       Impact factor: 84.694

3.  Membrane sorting of toll-like receptor (TLR)-2/6 and TLR2/1 heterodimers at the cell surface determines heterotypic associations with CD36 and intracellular targeting.

Authors:  Martha Triantafilou; Frederick G J Gamper; Rowenna M Haston; Marios Angelos Mouratis; Siegfried Morath; Thomas Hartung; Kathy Triantafilou
Journal:  J Biol Chem       Date:  2006-07-31       Impact factor: 5.157

4.  The inflammatory hypothesis: any progress in risk stratification and therapeutic targets?

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Journal:  Circulation       Date:  2006-10-10       Impact factor: 29.690

5.  An essential role of the NF-kappa B/Toll-like receptor pathway in induction of inflammatory and tissue-repair gene expression by necrotic cells.

Authors:  M Li; D F Carpio; Y Zheng; P Bruzzo; V Singh; F Ouaaz; R M Medzhitov; A A Beg
Journal:  J Immunol       Date:  2001-06-15       Impact factor: 5.422

6.  Local overexpression of toll-like receptors at the vessel wall induces atherosclerotic lesion formation: synergism of TLR2 and TLR4.

Authors:  Masakazu Shinohara; Ken-ichi Hirata; Tomoya Yamashita; Tomofumi Takaya; Naoto Sasaki; Rio Shiraki; Tomomi Ueyama; Noriaki Emoto; Nobutaka Inoue; Mitsuhiro Yokoyama; Seinosuke Kawashima
Journal:  Arterioscler Thromb Vasc Biol       Date:  2007-09-13       Impact factor: 8.311

7.  Flow-dependent regulation of endothelial Toll-like receptor 2 expression through inhibition of SP1 activity.

Authors:  Stefan Dunzendorfer; Hyun-Ku Lee; Peter S Tobias
Journal:  Circ Res       Date:  2004-09-02       Impact factor: 17.367

8.  Treatment of severe hypercholesterolemia in apolipoprotein E-deficient mice by bone marrow transplantation.

Authors:  W A Boisvert; J Spangenberg; L K Curtiss
Journal:  J Clin Invest       Date:  1995-08       Impact factor: 14.808

9.  NOD2 and toll-like receptors are nonredundant recognition systems of Mycobacterium tuberculosis.

Authors:  Gerben Ferwerda; Stephen E Girardin; Bart-Jan Kullberg; Lionel Le Bourhis; Dirk J de Jong; Dennis M L Langenberg; Reinout van Crevel; Gosse J Adema; Tom H M Ottenhoff; Jos W M Van der Meer; Mihai G Netea
Journal:  PLoS Pathog       Date:  2005-11-25       Impact factor: 6.823

Review 10.  Mechanisms of disease: genetic causes of familial hypercholesterolemia.

Authors:  Anne K Soutar; Rossi P Naoumova
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  5 in total

1.  Cutting edge: TLR2 is a functional receptor for acute-phase serum amyloid A.

Authors:  Ni Cheng; Rong He; Jun Tian; Patrick P Ye; Richard D Ye
Journal:  J Immunol       Date:  2008-07-01       Impact factor: 5.422

Review 2.  Innate and adaptive immunity in atherosclerosis.

Authors:  René R S Packard; Andrew H Lichtman; Peter Libby
Journal:  Semin Immunopathol       Date:  2009-05-16       Impact factor: 9.623

3.  Evaluation of Toll-Like receptor 2 and 4 RNA expression and the cytokine profile in postmenopausal women with metabolic syndrome.

Authors:  Claudio Lera Orsatti; Eliana Aguiar Petri Nahas; Jorge Nahas-Neto; Fabio Lera Orsatti; Vanessa Innocenti Giorgi; Steven S Witkin
Journal:  PLoS One       Date:  2014-10-17       Impact factor: 3.240

Review 4.  Therapeutic targeting of Toll-like receptors for infectious and inflammatory diseases and cancer.

Authors:  Luke A J O'Neill; Clare E Bryant; Sarah L Doyle
Journal:  Pharmacol Rev       Date:  2009-05-27       Impact factor: 25.468

5.  Short-Term Postoperative Cognitive Dysfunction and Inflammatory Response in Patients Undergoing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: A Pilot Study.

Authors:  Hui Yu; Rui Dong; Yayuan Lu; Xi Yang; Chang Chen; Zongze Zhang; Mian Peng
Journal:  Mediators Inflamm       Date:  2017-11-09       Impact factor: 4.711

  5 in total

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