| Literature DB >> 18057758 |
Kazuhiko Hayashi1, Eiko Kujime, Hajime Katayama, Shigeki Sano, Yoshimitsu Nagao.
Abstract
In the imine aldol reactions of 1 with aromatic aldehydes using magnesium salts in the presence of amines, the threo/erythro ratios of products increased in the order Mg(ClO4)2>MgI2>MgBr2>MgCl2>Mg(OTf)2 and N,N,N',N'-tetramethylethylenediamine (TMEDA)>Et3N. This increase in the threo/erythro ratios of products was estimated to be caused by a retro-imine aldol reaction under thermodynamic control.Entities:
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Year: 2007 PMID： 18057758 DOI： 10.1248/cpb.55.1773
Source DB: PubMed Journal: Chem Pharm Bull (Tokyo) ISSN： 0009-2363 Impact factor: 1.645