OBJECTIVE: To determine the impact of immediate release Ritalin, given three times a day, on sleep quality and quantity in medication-naïve, newly diagnosed children with attention-deficit/hyperactivity disorder (ADHD). METHODS:Children (aged 6-12) rigorously diagnosed with ADHD (n = 21) underwent multiple measurement assessments (i.e., actigraphy, sleep diary, and questionnaires) during a 1-week baseline and then during a 3-week blinded randomized medication trial. RESULTS: Although the medication was effective in reducing ADHD symptoms, analyses of actigraphy and sleep diary data found statistically and clinically significant changes in the children's total sleep time and sleep onset latency in the medication compared to the no medication conditions. No effects on sleep were found based on the sleep questionnaire. CONCLUSIONS: Physicians and parents are encouraged to closely monitor children's sleep when treating ADHD with stimulant medication.
RCT Entities:
OBJECTIVE: To determine the impact of immediate release Ritalin, given three times a day, on sleep quality and quantity in medication-naïve, newly diagnosed children with attention-deficit/hyperactivity disorder (ADHD). METHODS:Children (aged 6-12) rigorously diagnosed with ADHD (n = 21) underwent multiple measurement assessments (i.e., actigraphy, sleep diary, and questionnaires) during a 1-week baseline and then during a 3-week blinded randomized medication trial. RESULTS: Although the medication was effective in reducing ADHD symptoms, analyses of actigraphy and sleep diary data found statistically and clinically significant changes in the children's total sleep time and sleep onset latency in the medication compared to the no medication conditions. No effects on sleep were found based on the sleep questionnaire. CONCLUSIONS: Physicians and parents are encouraged to closely monitor children's sleep when treating ADHD with stimulant medication.
Authors: Michael C Antle; Hester C van Diepen; Tom Deboer; Pardis Pedram; Rob Rodrigues Pereira; Johanna H Meijer Journal: Neuropsychopharmacology Date: 2012-07-04 Impact factor: 7.853
Authors: Sang Heon Lee; Wan Seok Seo; Hyung Mo Sung; Tae Young Choi; So Yeun Kim; So-Jeong Choi; Bon Hoon Koo; Jong Hun Lee Journal: Psychiatry Investig Date: 2012-11-12 Impact factor: 2.505
Authors: Jorge Mendoza; Hester C van Diepen; Rob Rodrigues Pereira; Johanna H Meijer Journal: Psychopharmacology (Berl) Date: 2018-05-18 Impact factor: 4.530