OBJECTIVE: To evaluate the spermatotoxicity of gold nanoparticles. DESIGN: Experimental study. SETTING: A university in Thailand. PATIENT(S): Single-donor fresh semen sample. INTERVENTION(S): A mixture of gold nanoparticle solution and semen was prepared and further analyzed. MAIN OUTCOME MEASURE(S): Spermatozoa appearance. RESULT(S): After mixing the semen with a gold nanoparticle solution, 25% of sperm were not motile. Penetration of gold nanoparticle into the sperm heads and tails was observed. CONCLUSION(S): Spermatotoxicity of the gold nanoparticle can be detected.
OBJECTIVE: To evaluate the spermatotoxicity of gold nanoparticles. DESIGN: Experimental study. SETTING: A university in Thailand. PATIENT(S): Single-donor fresh semen sample. INTERVENTION(S): A mixture of gold nanoparticle solution and semen was prepared and further analyzed. MAIN OUTCOME MEASURE(S): Spermatozoa appearance. RESULT(S): After mixing the semen with a gold nanoparticle solution, 25% of sperm were not motile. Penetration of gold nanoparticle into the sperm heads and tails was observed. CONCLUSION(S): Spermatotoxicity of the gold nanoparticle can be detected.
Authors: S G Skuridin; V A Dubinskaya; V M Rudoy; O V Dement'eva; S T Zakhidov; T L Marshak; V A Kuz'min; V I Popenko; Yu M Evdokimov Journal: Dokl Biochem Biophys Date: 2010 May-Jun Impact factor: 0.788
Authors: Leili Fatehi; Susan M Wolf; Jeffrey McCullough; Ralph Hall; Frances Lawrenz; Jeffrey P Kahn; Cortney Jones; Stephen A Campbell; Rebecca S Dresser; Arthur G Erdman; Christy L Haynes; Robert A Hoerr; Linda F Hogle; Moira A Keane; George Khushf; Nancy M P King; Efrosini Kokkoli; Gary Marchant; Andrew D Maynard; Martin Philbert; Gurumurthy Ramachandran; Ronald A Siegel; Samuel Wickline Journal: J Law Med Ethics Date: 2012 Impact factor: 1.718