| Literature DB >> 18054312 |
Jenni Durieux1, Andrew Dillin.
Abstract
Metabolic component depletion in model systems results in life-span extension, which has been difficult to reconcile with human metabolic pathologies. Recently, Rea et al. (2007) have shown that mitochondrial electron transport chain RNAi phenotypes in the worm C. elegans are dose dependent, providing an alternative view of mitochondrial function in longevity and metabolic diseases.Entities:
Mesh：
Substances：
Year: 2007 PMID： 18054312 DOI： 10.1016/j.cmet.2007.11.008
Source DB: PubMed Journal: Cell Metab ISSN： 1550-4131 Impact factor: 27.287