| Literature DB >> 18054127 |
Heather F Gidding1, Margaret Warlow, C Raina MacIntyre, Josephine Backhouse, Gwendolyn L Gilbert, Helen E Quinn, Peter B McIntyre.
Abstract
We compared the results of two national serosurveys in Australia to evaluate the impact of universal infant vaccination and school-based programs for adolescents. Immunity improved significantly overall, especially in 1-year-olds (40.0% versus 86%; p<0.0001); in adolescents it was significantly higher in regions with established school-based programs (56.6% versus 38.8%; p=0.0008). 6.1% of 1-59-year-olds were positive for HBcAb and 0.7% for HBsAg. We have demonstrated successful implementation of universal infant hepatitis B vaccination in Australia and that school-based programs for adolescents are effective. This experience should be applicable to low prevalence countries in northern Europe which have not implemented universal hepatitis B immunisation.Entities:
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Year: 2007 PMID： 18054127 DOI： 10.1016/j.vaccine.2007.07.046
Source DB: PubMed Journal: Vaccine ISSN： 0264-410X Impact factor: 3.641