| Literature DB >> 18053728 |
Nashira Campos Vieira1, Laila Salmen Espíndola, Jaime Martins Santana, Maria Leopoldina Veras, Otília Deusdênia Loiola Pessoa, Sávio Moita Pinheiro, Renata Mendonça de Araújo, Mary Anne Sousa Lima, Edilberto Rocha Silveira.
Abstract
Two hundred fifteen compounds isolated from plants of Northeastern Brazil flora have been assayed against epimastigote forms of Trypanosoma cruzi, using the tetrazolium salt MTT as an alternative method. Eight compounds belonging to four different species: Harpalyce brasiliana (Fabaceae), Acnistus arborescens and Physalis angulata (Solanaceae), and Cordia globosa (Boraginaceae) showed significant activity. Among them, a novel and a known pterocarpan, a chalcone, four withasteroids, and a meroterpene benzoquinone were the represented chemical classes.Entities:
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Year: 2007 PMID： 18053728 DOI： 10.1016/j.bmc.2007.11.027
Source DB: PubMed Journal: Bioorg Med Chem ISSN： 0968-0896 Impact factor: 3.641