J C Forbi1, A B Odetunde. 1. Virology laboratory, Innovative Biotech-Keffi, PO Box 30 Keffi, Nasarawa State,Nigeria. cforbi79@hotmail.com
Abstract
BACKGROUND: Over 20 million persons are infected with HTLV-I/II globally. The virus is endemic in Africa and it is also transmitted sexually. Continued identification of high risk groups is important for the control of the disease. OBJECTIVES: To determine the prevalence of HTLV infection amongst two highly sexually active groups, pregnant women and CSWs in South Western Nigeria. METHODS: Serum samples were tested for the presence of HTLV-I/II antibodies using the Vironostika HTLV-I/II micro ELISA system. RESULTS: A total of 364 serum samples collected from pregnant women, commercial sex worker (CSW) and secondary school students (control group) from Ibadan. While only 4 (5.1%) of 78 secondary school students (average age: 13 years) were reactive for HTLV infection, 20 (16.7%) of 120 pregnant women (average age: 26 years) and 38 (22.9%) of 166 CSWs (average age: 23 years) were found to have antibodies against HTLV in their sera. The results of this study thus show that HTLV infection is active in the population although higher in pregnant women (although not statistically significant) and CSWs (p>0.05). Pregnant women and CSWs are therefore at a higher risk of HTLV transmission than other members of the population. CONCLUSION: Routine screening for HTLV infection may go a long way to understanding the epidemiology of HTLV infection in Nigeria and subsequently provide tools for its prevention and control.
BACKGROUND: Over 20 million persons are infected with HTLV-I/II globally. The virus is endemic in Africa and it is also transmitted sexually. Continued identification of high risk groups is important for the control of the disease. OBJECTIVES: To determine the prevalence of HTLV infection amongst two highly sexually active groups, pregnant women and CSWs in South Western Nigeria. METHODS: Serum samples were tested for the presence of HTLV-I/II antibodies using the Vironostika HTLV-I/II micro ELISA system. RESULTS: A total of 364 serum samples collected from pregnant women, commercial sex worker (CSW) and secondary school students (control group) from Ibadan. While only 4 (5.1%) of 78 secondary school students (average age: 13 years) were reactive for HTLV infection, 20 (16.7%) of 120 pregnant women (average age: 26 years) and 38 (22.9%) of 166 CSWs (average age: 23 years) were found to have antibodies against HTLV in their sera. The results of this study thus show that HTLV infection is active in the population although higher in pregnant women (although not statistically significant) and CSWs (p>0.05). Pregnant women and CSWs are therefore at a higher risk of HTLV transmission than other members of the population. CONCLUSION: Routine screening for HTLV infection may go a long way to understanding the epidemiology of HTLV infection in Nigeria and subsequently provide tools for its prevention and control.
Authors: C M Costa; P Goubau; H F Liu; A M Vandamme; F M da Cunha; T J Santos; J Desmyter; H Carton Journal: AIDS Res Hum Retroviruses Date: 1995-02 Impact factor: 2.205
Authors: Graham P Taylor; Monique Bodéus; Françoise Courtois; Georg Pauli; Annarosa Del Mistro; Ana Machuca; Elizabeth Padua; Soren Andersson; Patrick Goubau; Luigi Chieco-Bianchi; Vincent Soriano; Joliette Coste; Anthony E Ades; Jonathan N Weber Journal: J Acquir Immune Defic Syndr Date: 2005-01-01 Impact factor: 3.731
Authors: D O Olaleye; L Bernstein; Z Sheng; C C Ekweozor; X Y Li; J Sullivan-Halley; S Rasheed Journal: Am J Trop Med Hyg Date: 1994-04 Impact factor: 2.345
Authors: Augustine Ejike Okoye; Obike Godswill Ibegbulam; Robinson Chukwudi Onoh; Paul Olisaemeka Ezeonu; Ngozi I Ugwu; Lucky Osaheni Lawani; Chukwudi Simon Anigbo; Charles E Nonyelu Journal: Int J Womens Health Date: 2014-09-18