Literature DB >> 18052070

Ruthenium-catalyzed cycloaddition of aryl azides and alkynes.

Lars Kyhn Rasmussen1, Brant C Boren, Valery V Fokin.   

Abstract

The formation of 1,5-disubstituted 1,2,3-triazoles from aryl azides and alkynes was readily accomplished using [Cp*RuCl]4 catalyst in dimethylformamide. It was also demonstrated that the reaction provided higher yields, cleaner product, and shorter reaction times when carried out under microwave irradiation.

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Year:  2007        PMID： 18052070     DOI： 10.1021/ol701912s

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  19 in total

Review 1.  Controlled microwave heating in modern organic synthesis: highlights from the 2004-2008 literature.

Authors:  C Oliver Kappe; Doris Dallinger
Journal:  Mol Divers       Date:  2009-04-21       Impact factor: 2.943

2.  Preparation of 1,5-Disubstituted 1,2,3-Triazoles via Ruthenium-catalyzed Azide Alkyne Cycloaddition.

Authors:  James S Oakdale; Valery V Fokin; Satoshi Umezaki; Tohru Fukuyama
Journal:  Organic Synth       Date:  2013-01-01

3.  Integrated and passive 1,2,3-triazolyl groups in fluorescent indicators for zinc(II) ions: thermodynamic and kinetic evaluations.

Authors:  J Tyler Simmons; John R Allen; Deborah R Morris; Ronald J Clark; Cathy W Levenson; Michael W Davidson; Lei Zhu
Journal:  Inorg Chem       Date:  2013-04-26       Impact factor: 5.165

Review 4.  Copper-catalyzed azide-alkyne cycloaddition (CuAAC) and beyond: new reactivity of copper(I) acetylides.

Authors:  Jason E Hein; Valery V Fokin
Journal:  Chem Soc Rev       Date:  2010-03-04       Impact factor: 54.564

5.  Transition-metal-free catalytic synthesis of 1,5-diaryl-1,2,3-triazoles.

Authors:  Sen W Kwok; Joseph R Fotsing; Rebecca J Fraser; Valentin O Rodionov; Valery V Fokin
Journal:  Org Lett       Date:  2010-10-01       Impact factor: 6.005

6.  An aldol-based build/couple/pair strategy for the synthesis of medium- and large-sized rings: discovery of macrocyclic histone deacetylase inhibitors.

Authors:  Lisa A Marcaurelle; Eamon Comer; Sivaraman Dandapani; Jeremy R Duvall; Baudouin Gerard; Sarathy Kesavan; Maurice D Lee; Haibo Liu; Jason T Lowe; Jean-Charles Marie; Carol A Mulrooney; Bhaumik A Pandya; Ann Rowley; Troy D Ryba; Byung-Chul Suh; Jingqiang Wei; Damian W Young; Lakshmi B Akella; Nathan T Ross; Yan-Ling Zhang; Daniel M Fass; Surya A Reis; Wen-Ning Zhao; Stephen J Haggarty; Michelle Palmer; Michael A Foley
Journal:  J Am Chem Soc       Date:  2010-11-10       Impact factor: 15.419

7.  Ruthenium-catalyzed cycloadditions of 1-haloalkynes with nitrile oxides and organic azides: synthesis of 4-haloisoxazoles and 5-halotriazoles.

Authors:  James S Oakdale; Rakesh K Sit; Valery V Fokin
Journal:  Chemistry       Date:  2014-07-24       Impact factor: 5.236

8.  Probing the bioactive conformation of an archetypal natural product HDAC inhibitor with conformationally homogeneous triazole-modified cyclic tetrapeptides.

Authors:  W Seth Horne; Christian A Olsen; John M Beierle; Ana Montero; M Reza Ghadiri
Journal:  Angew Chem Int Ed Engl       Date:  2009       Impact factor: 15.336

9.  Probing gorge dimensions of cholinesterases by freeze-frame click chemistry.

Authors:  Zoran Radić; Roman Manetsch; Didier Fournier; K Barry Sharpless; Palmer Taylor
Journal:  Chem Biol Interact       Date:  2008-05-08       Impact factor: 5.192

10.  Synthesis of Mono- and Bisperoxide-Bridged Artemisinin Dimers to Elucidate the Contribution of Dimerization to Antimalarial Activity.

Authors:  Cynthia L Lichorowic; Yingzhao Zhao; Steven P Maher; Vivian Padín-Irizarry; Victoria C Mendiola; Sagan T de Castro; Jacob A Worden; Debora Casandra; Dennis E Kyle; Roman Manetsch
Journal:  ACS Infect Dis       Date:  2021-04-01       Impact factor: 5.578
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