Literature DB >> 18042695

Molecular aspects of HTLV-I infection and adult T-cell leukaemia/lymphoma.

G Taylor1.   

Abstract

Human T-cell lymphotropic virus-I (HTLV-I) is the cause of adult T-cell leukaemia/lymphoma. Various viral proteins, especially, but not exclusively, Tax have been implicated in oncogenesis, mostly through in vitro studies. Tax transactivates a large and apparently ever expanding list of human genes through transcriptional factors. Elucidating not only the pathways but also the timing of action of HTLV proteins is important for understanding the pathogenesis and development of new treatments.

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Year:  2007        PMID： 18042695      PMCID： PMC2095577          DOI： 10.1136/jcp.2007.052662

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN： 0021-9746            Impact factor:   3.411


  88 in total

1.  Suppression of DNA repair by human T cell leukemia virus type 1 Tax is rescued by a functional p53 signaling pathway.

Authors:  S Y Kao; F J Lemoine; S J Marriott
Journal:  J Biol Chem       Date:  2000-11-17       Impact factor: 5.157

2.  Stat5 and Sp1 regulate transcription of the cyclin D2 gene in response to IL-2.

Authors:  A Martino; J H Holmes; J D Lord; J J Moon; B H Nelson
Journal:  J Immunol       Date:  2001-02-01       Impact factor: 5.422

3.  trans activation of the tumor necrosis factor alpha promoter by the human T-cell leukemia virus type I Tax1 protein.

Authors:  H Albrecht; A N Shakhov; C V Jongeneel
Journal:  J Virol       Date:  1992-10       Impact factor: 5.103

4.  Transactivation of the c-myc promoter by human T cell leukemia virus type 1 tax is mediated by NF kappa B.

Authors:  M P Duyao; D J Kessler; D B Spicer; C Bartholomew; J L Cleveland; M Siekevitz; G E Sonenshein
Journal:  J Biol Chem       Date:  1992-08-15       Impact factor: 5.157

5.  Human T cell lymphotropic virus type I Tax activates IL-15R alpha gene expression through an NF-kappa B site.

Authors:  J M Mariner; V Lantz; T A Waldmann; N Azimi
Journal:  J Immunol       Date:  2001-02-15       Impact factor: 5.422

6.  Human T-cell leukemia virus type 1 tax protein activates transcription through AP-1 site by inducing DNA binding activity in T cells.

Authors:  K Iwai; N Mori; M Oie; N Yamamoto; M Fujii
Journal:  Virology       Date:  2001-01-05       Impact factor: 3.616

7.  In vitro and in vivo functional analysis of human T cell lymphotropic virus type 1 pX open reading frames I and II.

Authors:  M D Lairmore; B Albrecht; C D'Souza; J W Nisbet; W Ding; J T Bartoe; P L Green; W Zhang
Journal:  AIDS Res Hum Retroviruses       Date:  2000-11-01       Impact factor: 2.205

8.  The interleukin-2 receptor: a target for monoclonal antibody treatment of human T-cell lymphotrophic virus I-induced adult T-cell leukemia.

Authors:  T A Waldmann; J D White; C K Goldman; L Top; A Grant; R Bamford; E Roessler; I D Horak; S Zaknoen; C Kasten-Sportes
Journal:  Blood       Date:  1993-09-15       Impact factor: 22.113

9.  Role of human T-cell leukemia virus type 1 X region proteins in immortalization of primary human lymphocytes in culture.

Authors:  R Grassmann; S Berchtold; I Radant; M Alt; B Fleckenstein; J G Sodroski; W A Haseltine; U Ramstedt
Journal:  J Virol       Date:  1992-07       Impact factor: 5.103

10.  Extracellular Tax1 protein stimulates tumor necrosis factor-beta and immunoglobulin kappa light chain expression in lymphoid cells.

Authors:  P F Lindholm; R L Reid; J N Brady
Journal:  J Virol       Date:  1992-03       Impact factor: 5.103
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  4 in total

1.  Multiple Pathways Control the Reactivation of Telomerase in HTLV-I-Associated Leukemia.

Authors:  Marcia Bellon; Christophe Nicot
Journal:  Int J Cancer Oncol       Date:  2015-06-02

Review 2.  Adult T-cell leukaemia/lymphoma.

Authors:  E Matutes
Journal:  J Clin Pathol       Date:  2007-12       Impact factor: 3.411

3.  Tax impairs DNA replication forks and increases DNA breaks in specific oncogenic genome regions.

Authors:  Hassiba Chaib-Mezrag; Delphine Lemaçon; Hélène Fontaine; Marcia Bellon; Xue Tao Bai; Marjorie Drac; Arnaud Coquelle; Christophe Nicot
Journal:  Mol Cancer       Date:  2014-09-04       Impact factor: 27.401

4.  Absence of FLT3 mutations in Iranian adult T-cell leukemia/lymphoma patients.

Authors:  Hossein Ayatollahi; Mohammadhadi Sadeghian; Mohammadmahdi Kooshyar; Abass Shirdel; Hossein Rahimi; Amirhossein Jafarian; Saeide Ghazaei; Narges Soltani; Fatemeh Shams; Neda Motamedi Rad; Sepideh Shakeri
Journal:  Med J Islam Repub Iran       Date:  2018-06-09
  4 in total

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