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Literature DB >> 18042385

Spermicidal bacteriocins: lacticin 3147 and subtilosin A.

Lara Silkin¹, Shereen Hamza, Susan Kaufman, Steven L Cobb, John C Vederas.

Abstract

Spermicidal compounds that also exhibit antimicrobial properties would be extremely attractive agents as they could be used to not only prevent unwanted pregnancy but also to combat the growing prevalence of sexually transmitted infections (STI). One class of compounds that are potential candidates for development of dual-acting contraceptive products are antimicrobial peptides (AMPs). Herein, we report preliminary studies carried out to investigate the spermicidal activity of two bacteriocins, lacticin 3147 and subtilosin A, on bovine, horse/pony, boar and rat sperm.

Entities: Chemical Species

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Year: 2007 PMID： 18042385 DOI： 10.1016/j.bmcl.2007.11.024

Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823

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Cited

12 in total

1. The radical SAM enzyme AlbA catalyzes thioether bond formation in subtilosin A.

Authors: Leif Flühe; Thomas A Knappe; Michael J Gattner; Antje Schäfer; Olaf Burghaus; Uwe Linne; Mohamed A Marahiel
Journal: Nat Chem Biol Date: 2012-02-26 Impact factor: 15.040

2. Elucidation of the Molecular Mechanisms of Action of the Natural Antimicrobial Peptide Subtilosin Against the Bacterial Vaginosis-associated Pathogen Gardnerella vaginalis.

Authors: Katia Sutyak Noll; Patrick J Sinko; Michael L Chikindas
Journal: Probiotics Antimicrob Proteins Date: 2011-03 Impact factor: 4.609

Review 3. Anti-infective properties of bacteriocins: an update.

Authors: Riadh Hammami; Benoit Fernandez; Christophe Lacroix; Ismail Fliss
Journal: Cell Mol Life Sci Date: 2012-10-30 Impact factor: 9.261

Review 4. Radical S-adenosylmethionine enzymes.

Authors: Joan B Broderick; Benjamin R Duffus; Kaitlin S Duschene; Eric M Shepard
Journal: Chem Rev Date: 2014-01-29 Impact factor: 60.622

5. Contraceptive Sperm Agglutinating Proteins Identified in Staphylococcus warneri, Natural Microflora of an Infertile Woman.

Authors: Neeraj Chandra Pant; Ravinder Singh; Aditi Chauhan; Vijaya Gupta; Ravimohan S Mavuduru; Vijay Prabha; Prince Sharma
Journal: Indian J Microbiol Date: 2018-11-08 Impact factor: 2.461

6. Natural antimicrobial peptides as promising anti-HIV candidates.

Authors: Guangshun Wang
Journal: Curr Top Pept Protein Res Date: 2012

Review 7. Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature.

Authors: Paul G Arnison; Mervyn J Bibb; Gabriele Bierbaum; Albert A Bowers; Tim S Bugni; Grzegorz Bulaj; Julio A Camarero; Dominic J Campopiano; Gregory L Challis; Jon Clardy; Paul D Cotter; David J Craik; Michael Dawson; Elke Dittmann; Stefano Donadio; Pieter C Dorrestein; Karl-Dieter Entian; Michael A Fischbach; John S Garavelli; Ulf Göransson; Christian W Gruber; Daniel H Haft; Thomas K Hemscheidt; Christian Hertweck; Colin Hill; Alexander R Horswill; Marcel Jaspars; Wendy L Kelly; Judith P Klinman; Oscar P Kuipers; A James Link; Wen Liu; Mohamed A Marahiel; Douglas A Mitchell; Gert N Moll; Bradley S Moore; Rolf Müller; Satish K Nair; Ingolf F Nes; Gillian E Norris; Baldomero M Olivera; Hiroyasu Onaka; Mark L Patchett; Joern Piel; Martin J T Reaney; Sylvie Rebuffat; R Paul Ross; Hans-Georg Sahl; Eric W Schmidt; Michael E Selsted; Konstantin Severinov; Ben Shen; Kaarina Sivonen; Leif Smith; Torsten Stein; Roderich D Süssmuth; John R Tagg; Gong-Li Tang; Andrew W Truman; John C Vederas; Christopher T Walsh; Jonathan D Walton; Silke C Wenzel; Joanne M Willey; Wilfred A van der Donk
Journal: Nat Prod Rep Date: 2013-01 Impact factor: 13.423