| Literature DB >> 18042383 |
Lyn H Jones1, Amy Randall, Carolyn Napier, Mike Trevethick, Sasha Sreckovic, Jessica Watson.
Abstract
The design and concise synthesis of a fluorescent tolterodine-BODIPY (boron dipyrromethene) conjugate is described which possesses potent antimuscarinic activity. This derivative illustrates proof-of-concept for the preparation of other useful fluorophoric antimuscarinic agents which have potential utility in receptor occupancy studies and high throughput screens.Entities:
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Year: 2007 PMID: 18042383 DOI: 10.1016/j.bmcl.2007.11.022
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN: 0960-894X Impact factor: 2.823