INTRODUCTION: We employed a diffusion-tensor (DT) imaging technique involving a single-shot echo-planar sequence in combination with parallel imaging for tractography of the lower spinal cord and assessed the feasibility of this technique. METHODS: Images were obtained at 1.5 T using a five-channel receiver coil. We used a single-shot echo-planar sequence with parallel imaging to acquire diffusion-weighted (DW) images in the axial plane with phase encoding in the right-left direction. A motion-probing gradient was applied in six directions with a b-value of 1,000 s/mm(2). The scan time was 5 min 15 s. On a reconstructed DW image in the sagittal plane, the spinal cord was included in a single region-of-interest to generate a tractogram of the entire cord in seven volunteers and nine patients with spinal canal stenosis or vertebral metastasis. RESULTS: In each subject, although the conus medullaris and cauda equina were continuously visualized, the cord was demonstrated as a bundle of tracts color-coded in the z-axis. Nerve roots were depicted showing color-coding in the x- and y-axes. In the patient group, displacement of the cord was depicted showing changes in the color of the cord. Displacement of the proximal nerve roots was also depicted in the two patients with vertebral metastasis. CONCLUSION: DT imaging using parallel imaging shows potential as a method for routine tractography of the lower spinal cord.
INTRODUCTION: We employed a diffusion-tensor (DT) imaging technique involving a single-shot echo-planar sequence in combination with parallel imaging for tractography of the lower spinal cord and assessed the feasibility of this technique. METHODS: Images were obtained at 1.5 T using a five-channel receiver coil. We used a single-shot echo-planar sequence with parallel imaging to acquire diffusion-weighted (DW) images in the axial plane with phase encoding in the right-left direction. A motion-probing gradient was applied in six directions with a b-value of 1,000 s/mm(2). The scan time was 5 min 15 s. On a reconstructed DW image in the sagittal plane, the spinal cord was included in a single region-of-interest to generate a tractogram of the entire cord in seven volunteers and nine patients with spinal canal stenosis or vertebral metastasis. RESULTS: In each subject, although the conus medullaris and cauda equina were continuously visualized, the cord was demonstrated as a bundle of tracts color-coded in the z-axis. Nerve roots were depicted showing color-coding in the x- and y-axes. In the patient group, displacement of the cord was depicted showing changes in the color of the cord. Displacement of the proximal nerve roots was also depicted in the two patients with vertebral metastasis. CONCLUSION:DT imaging using parallel imaging shows potential as a method for routine tractography of the lower spinal cord.
Authors: B P Murphy; G P Zientara; P S Huppi; S E Maier; P D Barnes; F A Jolesz; J J Volpe Journal: J Magn Reson Imaging Date: 2001-06 Impact factor: 4.813
Authors: Claudia A M Wheeler-Kingshott; Simon J Hickman; Geoffrey J M Parker; Olga Ciccarelli; Mark R Symms; David H Miller; Gareth J Barker Journal: Neuroimage Date: 2002-05 Impact factor: 6.556
Authors: Brian Fiani; Christian Noblett; Jacob Nanney; Thao Doan; Elisabeth Pennington; Ryan Jarrah; Erika Sarno; Daniel Nikolaidis Journal: Surg Neurol Int Date: 2020-09-05