| Literature DB >> 18039570 |
Maloy Kumar Parai1, Gautam Panda, Kumkum Srivastava, Sunil Kumar Puri.
Abstract
A new series of benzene and isoquinoline sulfonamide derivatives were synthesized by nucleophilic displacement reaction on benzene and isoquinoline sulfonyl chlorides by substituted amines (primary and secondary). The title compounds were evaluated for antimalarial activity against Plasmodium falciparum in vitro and showed MIC in the range of 2-50 microg/mL.Entities:
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Year: 2007 PMID： 18039570 DOI： 10.1016/j.bmcl.2007.11.038
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823