| Literature DB >> 18036535 |
D H Marchand1, L R Snyder, J W Dolan.
Abstract
A total of 371 reversed-phase columns have now been characterized in terms of selectivity, based on five solute-column interactions (the hydrophobic-subtraction model). The present study illustrates the use of these data for interpreting peak-tailing and column stability. New insights are also provided concerning column selectivity as a function of ligand and silica type, and the selection of columns for orthogonal separations is re-examined. Some suggestions for the quality control of reversed-phase columns during manufacture are offered.Entities:
Mesh:
Year: 2007 PMID: 18036535 DOI: 10.1016/j.chroma.2007.10.079
Source DB: PubMed Journal: J Chromatogr A ISSN: 0021-9673 Impact factor: 4.759