Literature DB >> 18036535

Characterization and applications of reversed-phase column selectivity based on the hydrophobic-subtraction model.

D H Marchand1, L R Snyder, J W Dolan.   

Abstract

A total of 371 reversed-phase columns have now been characterized in terms of selectivity, based on five solute-column interactions (the hydrophobic-subtraction model). The present study illustrates the use of these data for interpreting peak-tailing and column stability. New insights are also provided concerning column selectivity as a function of ligand and silica type, and the selection of columns for orthogonal separations is re-examined. Some suggestions for the quality control of reversed-phase columns during manufacture are offered.

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Year:  2007        PMID: 18036535     DOI: 10.1016/j.chroma.2007.10.079

Source DB:  PubMed          Journal:  J Chromatogr A        ISSN: 0021-9673            Impact factor:   4.759


  6 in total

1.  Novel ultra stable silica-based stationary phases for reversed phase liquid chromatography--study of a hydrophobically assisted weak acid cation exchange phase.

Authors:  Yu Zhang; Peter W Carr
Journal:  J Chromatogr A       Date:  2010-11-16       Impact factor: 4.759

2.  Retention projection enables accurate calculation of liquid chromatographic retention times across labs and methods.

Authors:  Daniel Abate-Pella; Dana M Freund; Yan Ma; Yamil Simón-Manso; Juliane Hollender; Corey D Broeckling; David V Huhman; Oleg V Krokhin; Dwight R Stoll; Adrian D Hegeman; Tobias Kind; Oliver Fiehn; Emma L Schymanski; Jessica E Prenni; Lloyd W Sumner; Paul G Boswell
Journal:  J Chromatogr A       Date:  2015-08-03       Impact factor: 4.759

3.  Instrument parameters controlling retention precision in gradient elution reversed-phase liquid.

Authors:  Ayse Beyaza; Wenzhe Fana; Peter W Carr; Adam P Schellinger
Journal:  J Chromatogr A       Date:  2014-12-05       Impact factor: 4.759

4.  Application of Snyder-Dolan classification scheme to the selection of "orthogonal" columns for fast screening of illicit drugs and impurity profiling of pharmaceuticals--I. Isocratic elution.

Authors:  Wenzhe Fan; Yu Zhang; Peter W Carr; Sarah C Rutan; Melanie Dumarey; Adam P Schellinger; Wayne Pritts
Journal:  J Chromatogr A       Date:  2009-08-06       Impact factor: 4.759

5.  A visual approach to stationary phase selectivity classification based on the Snyder-Dolan Hydrophobic-Subtraction Model.

Authors:  Yu Zhang; Peter W Carr
Journal:  J Chromatogr A       Date:  2009-06-21       Impact factor: 4.759

Review 6.  Recent applications of retention modelling in liquid chromatography.

Authors:  Mimi J den Uijl; Peter J Schoenmakers; Bob W J Pirok; Maarten R van Bommel
Journal:  J Sep Sci       Date:  2020-11-03       Impact factor: 3.645

  6 in total

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