| Literature DB >> 18035546 |
Paulino Delgado-Méndez1, Nora Herrera, Haydee Chávez, Ana Estévez-Braun, Angel G Ravelo, Fernando Cortes, Santiago Castanys, Francisco Gamarro.
Abstract
Two new sesquiterpenes (1-2) and one new lupane triterpene (3) have been isolated from the roots of Maytenus apurimacensis. The novel beta-dihydroagarofurans are the first sesquiterpenes with a basic polyhydroxy skeleton of 15-deoxyalatol and 4,15-dideoxyalatol that show high MDR reversing activity in the protozoan parasite Leishmania tropica.Entities:
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Year: 2007 PMID： 18035546 DOI： 10.1016/j.bmc.2007.10.071
Source DB: PubMed Journal: Bioorg Med Chem ISSN： 0968-0896 Impact factor: 3.641