Literature DB >> 18034069

Morphine or bupivacaine in controlling postoperative pain in patients subjected to knee joint arthroscopy.

A Grabowska-Gaweł1, K Gaweł, W Hagner, P J Biliński.   

Abstract

Background. We investigated the efficacy of intra - articular bupivacaine with morphine administration after knee joint arthroscopy.<br /> Material and methods. The present study compared intra- arthicular bupivacaine with intra-arthricular morphine for postoperative analgesia in 56 patients (21 women, 35 men) (age 20-70, mean 39.8) undergoing knee joint arthroscopy.<br /> Intraoperatively, the patients received anaesthesia spinaly (0.5 % Marcaine spinal ASTRA) and immediately following surgery received 10 ml intra-arthricular injection consisting either of 0.5 % bupivacaine (group I), 5 mg morphine + 0.9 % saline (group II).Postoperative analgesia was supporeted by intravenous doses of proefferalgan.<br /> In all patients the visual analogue pain score (VAS), PaO2, systolic blood preassure (SABP), diastolic blood preassure (DABP), heart rate (HR), respiratory rate (f), supplemented analgesia and possible side effects were monitored postoperatively.<br /> Results. Intra-arthricular administration of each solution was well toleratede and non side effects were noted.<br /> There was non significant difference among the two groups in monitored parameters. The mean time of postoperative analgesia was 185,7 +/- 25.3 min for bupivacaine group and 390.3 +/- 35,4 min for morphine group.<br /> Total amount proefferalgan supplamentation was the highest in group I.<br /> Conclusions. Postoperative intra- arthricular injections of bupivacaine and morphine for patients undergoing knee joint arthroscopy can provide a safe and effective analgesia and therefore shound be recommended and widely implamented into the clinical use as a standard procedure.

Entities:  

Year:  2003        PMID: 18034069

Source DB:  PubMed          Journal:  Ortop Traumatol Rehabil        ISSN: 1509-3492


  4 in total

Review 1.  Single-dose intra-articular bupivacaine after knee arthroscopic surgery: a meta-analysis of randomized placebo-controlled studies.

Authors:  Jie Wei; Hao-bin Yang; Jia-bi Qin; Fan-jing Kong; Tu-bao Yang
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2013-06-09       Impact factor: 4.342

2.  In vitro assessment of human chondrocyte viability after treatment with local anaesthetic, magnesium sulphate or normal saline.

Authors:  J F Baker; P M Walsh; D P Byrne; K J Mulhall
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2011-02-18       Impact factor: 4.342

3.  Preemptive analgesia with intra-articular pethidine reduces pain after arthroscopic knee surgery.

Authors:  Sayed Jalal Hashemi; Hasanali Soltani; Sayed Morteza Heidari; Mahmoud Rezakohanfekr
Journal:  Adv Biomed Res       Date:  2013-03-06

4.  Local anaesthetics or their combination with morphine and/or magnesium sulphate are toxic for equine chondrocytes and synoviocytes in vitro.

Authors:  L M Rubio-Martínez; E Rioja; M Castro Martins; S Wipawee; P Clegg; M J Peffers
Journal:  BMC Vet Res       Date:  2017-11-07       Impact factor: 2.741

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.