Exophytic ulcerated tumors in HIV patients: diagnostic and therapeutic problems.

Two HIV-positive male patients with a rarely documented form of genital herpes are described. In both cases the atypical clinical presentation suggested neoplastic rather than infectious lesions. This tumorous genital herpes may occur in HIV-infected patients while on antiretroviral therapy. Since therapeutic failure to nucleoside analogues is common in these cases even in the absence of phenotypical resistance, other treatment options are discussed. (c) 2008 S. Karger AG, Basel.