Literature DB >> 18032624

Hidden VIM-1 metallo-beta-lactamase phenotypes among Acinetobacter baumannii clinical isolates.

Alexandros Ikonomidis1, Eleni Ntokou, Antonios N Maniatis, Athanassios Tsakris, Spyros Pournaras.   

Abstract

A total of 87 Acinetobacter baumannii nonrepetitive consecutive clinical isolates were tested for the presence of metallo-beta-lactamases (MBLs). Results of phenotypic assays (MBL Etest, imipenem/imipenem-EDTA combined-disk test, and imipenem/EDTA double-disk synergy test) were negative in all cases, but molecular testing revealed the presence of two bla(VIM-1)-carrying isolates. One isolate had bla(VIM-1) preceded by a weak P1 promoter, and both had inactivated P2 promoters and reduced bla(VIM-1) expression, partially justifying the results revealing hidden MBL phenotypes.

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Year:  2007        PMID： 18032624      PMCID： PMC2224304          DOI： 10.1128/JCM.01670-07

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  15 in total

1.  Outbreak of multiple clones of imipenem-resistant Acinetobacter baumannii isolates expressing OXA-58 carbapenemase in an intensive care unit.

Authors:  S Pournaras; A Markogiannakis; A Ikonomidis; L Kondyli; K Bethimouti; A N Maniatis; N J Legakis; A Tsakris
Journal:  J Antimicrob Chemother       Date:  2006-01-23       Impact factor: 5.790

2.  Outbreaks in distinct regions due to a single Klebsiella pneumoniae clone carrying a bla VIM-1 metallo-{beta}-lactamase gene.

Authors:  Alexandros Ikonomidis; Despina Tokatlidou; Ioulia Kristo; Danai Sofianou; Athanassios Tsakris; Paraskevi Mantzana; Spyros Pournaras; Antonios N Maniatis
Journal:  J Clin Microbiol       Date:  2005-10       Impact factor: 5.948

3.  Novel acquired metallo-beta-lactamase gene, bla(SIM-1), in a class 1 integron from Acinetobacter baumannii clinical isolates from Korea.

Authors:  Kyungwon Lee; Jong Hwa Yum; Dongeun Yong; Hyuk Min Lee; Heung Dong Kim; Jean-Denis Docquier; Gian Maria Rossolini; Yunsop Chong
Journal:  Antimicrob Agents Chemother       Date:  2005-11       Impact factor: 5.191

Review 4.  Metallo-beta-lactamases: the quiet before the storm?

Authors:  Timothy R Walsh; Mark A Toleman; Laurent Poirel; Patrice Nordmann
Journal:  Clin Microbiol Rev       Date:  2005-04       Impact factor: 26.132

5.  Metallo-beta-lactamases in clinical Pseudomonas isolates in Taiwan and identification of VIM-3, a novel variant of the VIM-2 enzyme.

Authors:  J J Yan; P R Hsueh; W C Ko; K T Luh; S H Tsai; H M Wu; J J Wu
Journal:  Antimicrob Agents Chemother       Date:  2001-08       Impact factor: 5.191

6.  Dissemination of the metallo-beta-lactamase gene blaIMP-4 among gram-negative pathogens in a clinical setting in Australia.

Authors:  Anton Y Peleg; Clare Franklin; Jan M Bell; Denis W Spelman
Journal:  Clin Infect Dis       Date:  2005-10-31       Impact factor: 9.079

7.  Prevalence of metallo-beta-lactamase among Pseudomonas aeruginosa and Acinetobacter baumannii in a Korean university hospital and comparison of screening methods for detecting metallo-beta-lactamase.

Authors:  Eun-Jee Oh; Seungok Lee; Yeon-Joon Park; Jung Jun Park; Kanggyun Park; Sang-Il Kim; Moon Won Kang; Byung Kee Kim
Journal:  J Microbiol Methods       Date:  2003-09       Impact factor: 2.363

8.  Expression of antibiotic resistance genes in the integrated cassettes of integrons.

Authors:  C M Collis; R M Hall
Journal:  Antimicrob Agents Chemother       Date:  1995-01       Impact factor: 5.191

9.  A highly carbapenem-resistant Pseudomonas aeruginosa isolate with a novel blaVIM-4/blaP1b integron overexpresses two efflux pumps and lacks OprD.

Authors:  Maria Maniati; Alexandros Ikonomidis; Paraskevi Mantzana; Alexandros Daponte; Antonios N Maniatis; Spyros Pournaras
Journal:  J Antimicrob Chemother       Date:  2007-05-04       Impact factor: 5.790

10.  VIM-1 metallo-beta-lactamase in Acinetobacter baumannii.

Authors:  Athanassios Tsakris; Alexandros Ikonomidis; Spyros Pournaras; Leonidas S Tzouvelekis; Danai Sofianou; Nicholas J Legakis; Antonios N Maniatis
Journal:  Emerg Infect Dis       Date:  2006-06       Impact factor: 6.883
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  10 in total

1.  Outbreak of Acinetobacter baumannii with chromosomally encoded VIM-1 undetectable by imipenem-EDTA synergy tests.

Authors:  Alexandra Loli; Leonidas S Tzouvelekis; Dimitra Gianneli; Eva Tzelepi; Vivi Miriagou
Journal:  Antimicrob Agents Chemother       Date:  2008-02-19       Impact factor: 5.191

2.  Detection of VIM- and IMP-type Metallo-Beta-Lactamase Genes in Acinetobacter baumannii Isolates from Patients in Two Hospitals in Tehran.

Authors:  Saba Davoodi; Mohammad Ali Boroumand; Saeed Sepehriseresht; Leila Pourgholi
Journal:  Iran J Biotechnol       Date:  2015-03       Impact factor: 1.671

3.  Emergence of VIM-12 in Enterobacter cloacae.

Authors:  Maria Panopoulou; Eleonora Alepopoulou; Alexandros Ikonomidis; Anastasia Grapsa; Eleni Paspalidou; Sofia Kartali-Ktenidou
Journal:  J Clin Microbiol       Date:  2010-06-30       Impact factor: 5.948

4.  Infections with VIM-1 metallo-{beta}-lactamase-producing enterobacter cloacae and their correlation with clinical outcome.

Authors:  Marco Falcone; Maria Lina Mezzatesta; Mariagrazia Perilli; Chiara Forcella; Alessandra Giordano; Viviana Cafiso; Gianfranco Amicosante; Stefania Stefani; Mario Venditti
Journal:  J Clin Microbiol       Date:  2009-09-09       Impact factor: 5.948

5.  Isolation and genetic characterization of metallo-β-lactamase and carbapenamase producing strains of Acinetobacter baumannii from patients at Tehran hospitals.

Authors:  F Shahcheraghi; M Abbasalipour; Mm Feizabadi; Gh Ebrahimipour; N Akbari
Journal:  Iran J Microbiol       Date:  2011-06

Review 6.  Epidemiology of carbapenemase-producing Enterobacteriaceae and Acinetobacter baumannii in Mediterranean countries.

Authors:  Nassima Djahmi; Catherine Dunyach-Remy; Alix Pantel; Mazouz Dekhil; Albert Sotto; Jean-Philippe Lavigne
Journal:  Biomed Res Int       Date:  2014-05-13       Impact factor: 3.411

7.  Association of the genes encoding Metallo-β-Lactamase with the presence of integrons among multidrug-resistant clinical isolates of Acinetobacter baumannii.

Authors:  Mansour Amin; Tahereh Navidifar; Farkhondeh Saleh Shooshtari; Hamed Goodarzi
Journal:  Infect Drug Resist       Date:  2019-05-13       Impact factor: 4.003

8.  Bacterial colonization dynamics and antibiotic resistance gene dissemination in the hospital environment after first patient occupancy: a longitudinal metagenetic study.

Authors:  Tilman E Klassert; Rasmus Leistner; Cristina Zubiria-Barrera; Magdalena Stock; Mercedes López; Robert Neubert; Dominik Driesch; Petra Gastmeier; Hortense Slevogt
Journal:  Microbiome       Date:  2021-08-11       Impact factor: 14.650

9.  Control of a Multi-Drug-Resistant Acinetobacter baumannii Outbreak after Orthopedics Department Relocation.

Authors:  Vasiliki Gogou; Georgios Meletis; Dimosthenis Tsitouras
Journal:  Microorganisms       Date:  2013-12-02

Review 10.  Acinetobacter baumannii Antibiotic Resistance Mechanisms.

Authors:  Ioannis Kyriakidis; Eleni Vasileiou; Zoi Dorothea Pana; Athanasios Tragiannidis
Journal:  Pathogens       Date:  2021-03-19
  10 in total

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