Literature DB >> 18032401

A qualitative study of patient views on discontinuing long-term selective serotonin reuptake inhibitors.

Geraldine M Leydon1, Lynne Rodgers, Tony Kendrick.   

Abstract

BACKGROUND: There is concern that patients may be remaining on selective serotonin reuptake inhibitors (SSRIs) longer than is clinically indicated. Previous research has explored patients' experiences of taking SSRIs and decisions about starting medication. There has been less research into patients' reasons for long-term use and their views and experiences of discontinuation. AIM: To explore patient experiences of and beliefs about their long-standing SSRI use and understand the barriers and facilitators to discontinuation.
DESIGN: Face-to-face semi-structured qualitative interview study.
SETTING: One group general practice in Southampton, UK.
FINDINGS: Three overarching themes were identified: (i) patient uncertainty about the benefits of, and continued need for, SSRI medication; (ii) barriers to stopping, including fear of withdrawal symptoms and fear of relapse; and (iii) the importance of the GP's role in facilitating cessation. Uncertainty and fear about withdrawal symptoms and what patients would be like without their medication were key barriers to stopping, even among patients who felt no discernible benefit from taking SSRIs. Patients indicated a need to share the decision to stop with their GP. However, the majority of patients interviewed had received repeat prescriptions of SSRIs without being reviewed by the GP.
CONCLUSIONS: Patients prescribed SSRI medication need to be reassured that, as with starting medication, thinking about or actually stopping medication is a task that will not be managed in isolation, but with the support of their GP.

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Year:  2007        PMID: 18032401     DOI: 10.1093/fampra/cmm069

Source DB:  PubMed          Journal:  Fam Pract        ISSN: 0263-2136            Impact factor:   2.267


  24 in total

1.  Long-term prescribing of antidepressants in the older population: a qualitative study.

Authors:  Rebecca Dickinson; Peter Knapp; Allan O House; Vandana Dimri; Arnold Zermansky; Duncan Petty; John Holmes; David K Raynor
Journal:  Br J Gen Pract       Date:  2010-04       Impact factor: 5.386

2.  Predicting and preventing relapse of depression in primary care.

Authors:  Andrew S Moriarty; Joanne Castleton; Simon Gilbody; Dean McMillan; Shehzad Ali; Richard D Riley; Carolyn A Chew-Graham
Journal:  Br J Gen Pract       Date:  2020-01-30       Impact factor: 5.386

3.  Perceptions of Statin Discontinuation among Patients with Life-Limiting Illness.

Authors:  Jennifer Tjia; Jean S Kutner; Christine S Ritchie; Patrick J Blatchford; Rachael E Bennett Kendrick; Maryjo Prince-Paul; Tamara J Somers; Mary Lynn McPherson; Jeff A Sloan; Amy P Abernethy; Jon P Furuno
Journal:  J Palliat Med       Date:  2017-05-18       Impact factor: 2.947

Review 4.  Patient values and preferences on polypharmacy and deprescribing: a scoping review.

Authors:  Evan Forest; Melissa Ireland; Uma Yakandawala; Teresa Cavett; Lalitha Raman-Wilms; Jamie Falk; Diana McMillan; Rhys Linthorst; Leanne Kosowan; Lisa Labine; Christine Leong
Journal:  Int J Clin Pharm       Date:  2021-09-22

5.  Long-term antidepressant use: a qualitative study on perspectives of patients and GPs in primary care.

Authors:  Renske C Bosman; Klaas M Huijbregts; Peter Fm Verhaak; Henricus G Ruhé; Harm Wj van Marwijk; Anton Jlm van Balkom; Neeltje M Batelaan
Journal:  Br J Gen Pract       Date:  2016-08-15       Impact factor: 5.386

6.  Enhancing shared decision making about discontinuation of antidepressant medication: a concept-mapping study in primary and secondary mental health care.

Authors:  Carolien Wentink; Marloes J Huijbers; Peter Lbj Lucassen; Annoek van der Gouw; Cornelis Kramers; Jan Spijker; Anne Em Speckens
Journal:  Br J Gen Pract       Date:  2019-10-31       Impact factor: 5.386

Review 7.  Patient barriers to and enablers of deprescribing: a systematic review.

Authors:  Emily Reeve; Josephine To; Ivanka Hendrix; Sepehr Shakib; Michael S Roberts; Michael D Wiese
Journal:  Drugs Aging       Date:  2013-10       Impact factor: 3.923

8.  Patient attitudes and experiences that predict medication discontinuation in the Veterans Health Administration.

Authors:  Amy Linsky; Steven R Simon; Kelly Stolzmann; Mark Meterko
Journal:  J Am Pharm Assoc (2003)       Date:  2017-11-16

9.  Explaining the rise in antidepressant prescribing: a descriptive study using the general practice research database.

Authors:  Michael Moore; Ho Ming Yuen; Nick Dunn; Mark A Mullee; Joe Maskell; Tony Kendrick
Journal:  BMJ       Date:  2009-10-15

10.  Barricades and brickwalls--a qualitative study exploring perceptions of medication use and deprescribing in long-term care.

Authors:  Anna Palagyi; Lisa Keay; Jessica Harper; Jan Potter; Richard I Lindley
Journal:  BMC Geriatr       Date:  2016-01-15       Impact factor: 3.921

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