| Literature DB >> 18031693 |
Abstract
Toll-like receptor 7 (TLR7) detects viral RNA, but can be activated inappropriately by self-RNA, leading to autoimmunity. Deane et al. (2007) show that Tlr7 gene dosage is directly related to the risk of lupus in a mouse model.Entities:
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Year: 2007 PMID: 18031693 DOI: 10.1016/j.immuni.2007.11.001
Source DB: PubMed Journal: Immunity ISSN: 1074-7613 Impact factor: 31.745