Literature DB >> 18031056

Biaryl synthesis via palladium-catalyzed aryne multicomponent coupling.

Jaclyn L Henderson1, Andrew S Edwards, Michael F Greaney.   

Abstract

Aryl iodides have been introduced as electrophiles in the three-component Heck coupling of arynes. Following optimization studies to favor three- versus two-component coupling, the reaction proceeds in good yield to afford a variety of functionalized biaryls.

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Year:  2007        PMID： 18031056     DOI： 10.1021/ol702584t

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  7 in total

1.  Palladium-catalyzed annulation of arynes by o-halobenzamides: synthesis of phenanthridinones.

Authors:  Chun Lu; Anton V Dubrovskiy; Richard C Larock
Journal:  J Org Chem       Date:  2012-09-26       Impact factor: 4.354

2.  Base-mediated intermolecular sp2 C-H bond arylation via benzyne intermediates.

Authors:  Thanh Truong; Olafs Daugulis
Journal:  J Am Chem Soc       Date:  2011-03-08       Impact factor: 15.419

3.  Synthesis of 9-fluorenylidenes and 9,10-phenanthrenes through palladium-catalyzed aryne annulation by o-halostyrenes and o-halo allylic benzenes.

Authors:  Shilpa A Worlikar; Richard C Larock
Journal:  J Org Chem       Date:  2009-12-04       Impact factor: 4.354

4.  Pd(OAc)(2)-catalyzed domino reactions of 1,2-dihaloarenes and 2-haloaryl arenesulfonates with Grignard reagents: efficient synthesis of substituted fluorenes.

Authors:  Cheng-Guo Dong; Qiao-Sheng Hu
Journal:  Tetrahedron       Date:  2008-03-10       Impact factor: 2.457

5.  Palladium-catalyzed synthesis of 9-fluorenylidenes through aryne annulation.

Authors:  Shilpa A Worlikar; Richard C Larock
Journal:  Org Lett       Date:  2009-06-04       Impact factor: 6.005

6.  General method for functionalized polyaryl synthesis via aryne intermediates.

Authors:  Thanh Truong; Milad Mesgar; Ky Khac Anh Le; Olafs Daugulis
Journal:  J Am Chem Soc       Date:  2014-06-03       Impact factor: 15.419

7.  Metal Free Bi(hetero)aryl Synthesis: A Benzyne Truce-Smiles Rearrangement.

Authors:  Catherine M Holden; Shariar M A Sohel; Michael F Greaney
Journal:  Angew Chem Int Ed Engl       Date:  2016-01-13       Impact factor: 15.336
  7 in total

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