Literature DB >> 18030985

Bactericidal antibiotics and oxidative stress: a radical proposal.

Daniel J Hassett1, James A Imlay.   

Abstract

A recent publication suggests that many antibiotics exert their bactericidal effects via the production of hydroxyl radicals, regardless of their molecular targets. This proposal represents an abrupt departure from conventional models, and it will attract further experimental tests.

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Year:  2007        PMID： 18030985     DOI： 10.1021/cb700232k

Source DB:  PubMed          Journal:  ACS Chem Biol        ISSN： 1554-8929            Impact factor:   5.100


  21 in total

1.  Eradication of bacterial persisters with antibiotic-generated hydroxyl radicals.

Authors:  Sarah Schmidt Grant; Benjamin B Kaufmann; Nikhilesh S Chand; Nathan Haseley; Deborah T Hung
Journal:  Proc Natl Acad Sci U S A       Date:  2012-07-09       Impact factor: 11.205

2.  Deciphering the mode of action of the synthetic antimicrobial peptide Bac8c.

Authors:  E C Spindler; J D F Hale; T H Giddings; R E W Hancock; R T Gill
Journal:  Antimicrob Agents Chemother       Date:  2011-01-31       Impact factor: 5.191

3.  Role of autofluorescence in flow cytometric analysis of Escherichia coli treated with bactericidal antibiotics.

Authors:  Sabine Renggli; Wolfgang Keck; Urs Jenal; Daniel Ritz
Journal:  J Bacteriol       Date:  2013-07-08       Impact factor: 3.490

4.  Iron homeostasis affects antibiotic-mediated cell death in Pseudomonas species.

Authors:  Jinki Yeom; James A Imlay; Woojun Park
Journal:  J Biol Chem       Date:  2010-05-17       Impact factor: 5.157

5.  Generation of reactive oxygen species by lethal attacks from competing microbes.

Authors:  Tao G Dong; Shiqi Dong; Christy Catalano; Richard Moore; Xiaoye Liang; John J Mekalanos
Journal:  Proc Natl Acad Sci U S A       Date:  2015-02-02       Impact factor: 11.205

6.  Clarifying the role of two-component regulation in antibiotic killing.

Authors:  Colin Manoil
Journal:  J Bacteriol       Date:  2013-02-22       Impact factor: 3.490

7.  Antibiotic and ROS linkage questioned.

Authors:  Ferric C Fang
Journal:  Nat Biotechnol       Date:  2013-05       Impact factor: 54.908

8.  Silver Nanoparticles Against Salmonella enterica Serotype Typhimurium: Role of Inner Membrane Dysfunction.

Authors:  Minju Seong; Dong Gun Lee
Journal:  Curr Microbiol       Date:  2017-03-21       Impact factor: 2.188

9.  Mechanisms of hop inhibition include the transmembrane redox reaction.

Authors:  Jürgen Behr; Rudi F Vogel
Journal:  Appl Environ Microbiol       Date:  2009-10-30       Impact factor: 4.792

10.  The communication factor EDF and the toxin-antitoxin module mazEF determine the mode of action of antibiotics.

Authors:  Ilana Kolodkin-Gal; Boaz Sat; Alex Keshet; Hanna Engelberg-Kulka
Journal:  PLoS Biol       Date:  2008-12-16       Impact factor: 8.029
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