Literature DB >> 18030079

Prevalence and psychiatric comorbidity of attention-deficit/hyperactivity disorder in an adolescent Finnish population.

Susan L Smalley1, James J McGough, Irma K Moilanen, Sandra K Loo, Anja Taanila, Hanna Ebeling, Tuula Hurtig, Marika Kaakinen, Lorie A Humphrey, James T McCracken, Teppo Varilo, May H Yang, Stanley F Nelson, Leena Peltonen, Marjo-Riitta Järvelin.   

Abstract

OBJECTIVE: The purpose of the study was to estimate the prevalence of attention-deficit/hyperactivity disorder (ADHD) and its clinical characteristics in the Northern Finland Birth Cohort 1986.
METHOD: A general population Northern Finland Birth Cohort 1986 of 9,432 children followed prospectively from the early fetal period was surveyed at adolescence (ages 16-18) for ADHD behaviors. Among 6,622 respondents to the survey, a subset of 457 likely cases and controls were evaluated for ADHD and other psychiatric disorders. Chi-square and descriptive statistics were used to examine clinical characteristics of ADHD in the subset, and logistic regression was used to estimate prevalence by weighted extrapolation in the larger cohort.
RESULTS: The estimated prevalence of ADHD among adolescents in the Northern Finland Birth Cohort 1986 is 8.5% with a male/female ratio of 5.7:1. The distribution of ADHD subtypes among the ADHD adolescents is 28% Combined, 64% Inattentive, and 8% Hyperactive-Impulsive. A lifetime diagnosis of a broadly defined ADHD (probable or definite) had a prevalence of 18.2% with a male/female odds ratio (OR) of 3.2. This lifetime diagnosis of ADHD is significantly associated with anxiety (OR 2.4), mood (OR 2.9), and disruptive behavioral disorders (OR 17.3) in the cohort.
CONCLUSIONS: ADHD is a common neurobehavioral disorder among Northern Finnish adolescents and significantly associated with psychiatric comorbidity in adolescence.

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Year:  2007        PMID: 18030079     DOI: 10.1097/chi.0b013e3181573137

Source DB:  PubMed          Journal:  J Am Acad Child Adolesc Psychiatry        ISSN: 0890-8567            Impact factor:   8.829


  46 in total

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3.  ADHD and comorbid disorders in relation to family environment and symptom severity.

Authors:  Tuula Hurtig; Hanna Ebeling; Anja Taanila; Jouko Miettunen; Susan Smalley; James McGough; Sandra Loo; Marjo-Riitta Järvelin; Irma Moilanen
Journal:  Eur Child Adolesc Psychiatry       Date:  2007-03-30       Impact factor: 4.785

4.  Association of the cannabinoid receptor gene (CNR1) with ADHD and post-traumatic stress disorder.

Authors:  Ake T Lu; Matthew N Ogdie; Marjo-Ritta Järvelin; Irma K Moilanen; Sandra K Loo; James T McCracken; James J McGough; May H Yang; Leena Peltonen; Stanley F Nelson; Rita M Cantor; Susan L Smalley
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2008-12-05       Impact factor: 3.568

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Authors:  Jukka Savolainen; W Alex Mason; Jonathan D Bolen; Mary B Chmelka; Tuula Hurtig; Hanna Ebeling; Tanja Nordström; Anja Taanila
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9.  Associations between psychotic-like symptoms and inattention/hyperactivity symptoms.

Authors:  Tuula Marketta Hurtig; Anja Taanila; Juha Veijola; Hanna Ebeling; Pirjo Mäki; Jouko Miettunen; Marika Kaakinen; Matti Joukamaa; Sebastian Therman; Markus Heinimaa; Marjo-Riitta Järvelin; Irma Moilanen
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2009-11-12       Impact factor: 4.328

10.  Developmental sex differences in nicotinic currents of prefrontal layer VI neurons in mice and rats.

Authors:  Nyresa C Alves; Craig D C Bailey; Raad Nashmi; Evelyn K Lambe
Journal:  PLoS One       Date:  2010-02-17       Impact factor: 3.240

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