Literature DB >> 18029250

Cilia biology: stop overeating now!

Peter Satir1.   

Abstract

Knocking out primary cilia of adult mouse tissues or a specific subset of cilia from POMC-expressing neurons in the brain initiates uncontrolled eating. This behavior leads to obesity and kidney disease.

Entities:  

Mesh：

Year:  2007        PMID： 18029250     DOI： 10.1016/j.cub.2007.09.006

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  13 in total

1.  Obesity in patients with Bardet-Biedl syndrome: influence of appetite-regulating hormones.

Authors:  Anja K Büscher; Metin Cetiner; Rainer Büscher; Anne-Margret Wingen; Berthold P Hauffa; Peter F Hoyer
Journal:  Pediatr Nephrol       Date:  2012-06-05       Impact factor: 3.714

Review 2.  Mechanistic insights into Bardet-Biedl syndrome, a model ciliopathy.

Authors:  Norann A Zaghloul; Nicholas Katsanis
Journal:  J Clin Invest       Date:  2009-03-02       Impact factor: 14.808

Review 3.  The primary cilium at a glance.

Authors:  Peter Satir; Lotte B Pedersen; Søren T Christensen
Journal:  J Cell Sci       Date:  2010-02-15       Impact factor: 5.285

Review 4.  Alström syndrome: insights into the pathogenesis of metabolic disorders.

Authors:  Dorothée Girard; Nikolai Petrovsky
Journal:  Nat Rev Endocrinol       Date:  2010-12-07       Impact factor: 43.330

5.  Caloric restriction in Alström syndrome prevents hyperinsulinemia.

Authors:  Ni-Chung Lee; Jan D Marshall; Gayle B Collin; Jürgen K Naggert; Yin-Hsiu Chien; Wen-Yu Tsai; Wuh-Liang Hwu
Journal:  Am J Med Genet A       Date:  2009-02-15       Impact factor: 2.802

Review 6.  60 YEARS OF POMC: From POMC and α-MSH to PAM, molecular oxygen, copper, and vitamin C.

Authors:  Dhivya Kumar; Richard E Mains; Betty A Eipper
Journal:  J Mol Endocrinol       Date:  2015-12-14       Impact factor: 5.098

Review 7.  Structural studies of ciliary components.

Authors:  Naoko Mizuno; Michael Taschner; Benjamin D Engel; Esben Lorentzen
Journal:  J Mol Biol       Date:  2012-06-06       Impact factor: 5.469

8.  Characterization of an apical ceramide-enriched compartment regulating ciliogenesis.

Authors:  Qian He; Guanghu Wang; Somsankar Dasgupta; Michael Dinkins; Gu Zhu; Erhard Bieberich
Journal:  Mol Biol Cell       Date:  2012-06-20       Impact factor: 4.138

9.  Laminin-511 and integrin beta-1 in hair follicle development and basal cell carcinoma formation.

Authors:  Mindy C DeRouen; Hanson Zhen; Si Hui Tan; Samantha Williams; M Peter Marinkovich; Anthony E Oro
Journal:  BMC Dev Biol       Date:  2010-11-10       Impact factor: 1.978

10.  Primary ciliogenesis defects are associated with human astrocytoma/glioblastoma cells.

Authors:  Joanna J Moser; Marvin J Fritzler; Jerome B Rattner
Journal:  BMC Cancer       Date:  2009-12-17       Impact factor: 4.430
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