C K Axelsson1, P-E Jønsson. 1. Department of Breast Surgery, Herlev University Hospital, DK-2730 Herlev, Copenhagen, Denmark. c.axelsson@dadlnet.dk
Abstract
BACKGROUND: In a pilot prospective consecutive series on 50 patients with recurrent breast cancer, results of sentinel lymph node biopsy (SLNB) are reported. The interval between primary operation and recurrence was 8years (range 1-18years). Only three patients had not undergone dissection of the axilla (ALND). RESULTS: In 51% of patients scintigraphy disclosed sentinel nodes (SN). At operation SN was identified in 45% of patients corresponding to 83% of the SN's visualized by the scintigraphy. SN contained metastases in seven cases (16%), and the treatment plan was changed as a consequence of the SN examination. CONCLUSION: SLNB can identify SN at a high rate, and the findings may influence further planning of treatment. SLNB should be a future standard procedure in operations for recurrent breast cancer. Next step should be a randomized study.
BACKGROUND: In a pilot prospective consecutive series on 50 patients with recurrent breast cancer, results of sentinel lymph node biopsy (SLNB) are reported. The interval between primary operation and recurrence was 8years (range 1-18years). Only three patients had not undergone dissection of the axilla (ALND). RESULTS: In 51% of patients scintigraphy disclosed sentinel nodes (SN). At operation SN was identified in 45% of patients corresponding to 83% of the SN's visualized by the scintigraphy. SN contained metastases in seven cases (16%), and the treatment plan was changed as a consequence of the SN examination. CONCLUSION: SLNB can identify SN at a high rate, and the findings may influence further planning of treatment. SLNB should be a future standard procedure in operations for recurrent breast cancer. Next step should be a randomized study.
Authors: Lenka Vermeeren; Willem Meinhardt; Henk G van der Poel; Renato A Valdés Olmos Journal: Eur J Nucl Med Mol Imaging Date: 2010-07-09 Impact factor: 9.236
Authors: Diego A Vicente; Leonard R Henry; George Hahm; Peter W Soballe; DeeDee Smart Journal: World J Surg Oncol Date: 2010-07-09 Impact factor: 2.754