Literature DB >> 18028892

Investigation of the prevalence of CKD in 13,383 Chinese hospitalised adult patients.

Bi-Cheng Liu1, Xiao-Chun Wu, Yan-Li Wang, Bei Wang, Jun Gao, Qing-Juan Zhang, Ying Zhu, Xiao-Liang Zhang, Lian-Fang Yin.   

Abstract

BACKGROUND: There is an increase prevalence of chronic kidney disease (CKD)worldwide. However, the exact incidence of CKD in China is still uncertain. In this cross-sectional study, we retrospectively investigated the prevalence and distribution of CKD in Chinese hospitalised adult patients.
METHODS: Totally, 13,383 adults patients who were hospitalised at our hospital were included in this study. They included 6215 males and 7168 females. Patients' gender, age, blood pressure, serum creatinine, blood urea nitrogen, uric acid, triglyceride, total cholesterol, albumin, hemoglobin, hemotocrit, urine protein, and history of hypertension, diabetes, and smoking were investigated. CKD was defined as eGFR<60 ML/ MIN PER 1.73 m(2) and/or proteinuria, GFR was estimated by using of the simplified MDRD equation.
RESULTS: The prevalence rate of CKD was 14.82% in our group, which was respectively distributed from 1 to stage 5 at the following percentage, 3.33% (stage 1), 2.49% ( stage 2), 7.07% (stage 3), 1.08% (stage 4), and 0.86% (stage 5). Elderly patients (age >65 y) accounted for 53.07%, which had a higher CKD prevalence (29.47%) than middle and young-aged patients (9.49%). It was noted that 39.06% patients at stage 1-3 were undiagnosed with CKD during their hospitalization. The common etiology for CKD was hypertension (29.49%), diabetes (11.64%) and primary glomerulonephritis (4.39%). Hypertension, diabetes and ages were main associated factors for CKD.
CONCLUSIONS: CKD is a very common disease among the hospitalised patients in China. With the increasing of aging population, elderly people will be the highest risk group for CKD. More strategies have to be made for its early detection and prevention.

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Year:  2008        PMID: 18028892     DOI: 10.1016/j.cca.2007.09.020

Source DB:  PubMed          Journal:  Clin Chim Acta        ISSN: 0009-8981            Impact factor:   3.786


  7 in total

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2.  Are cystatin C-based equations superior to creatinine-based equations for estimating GFR in Chinese elderly population?

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Journal:  Cardiovasc Diagn Ther       Date:  2015-12

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Journal:  PLoS One       Date:  2021-02-04       Impact factor: 3.240

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7.  Aetiology of chronic kidney disease and risk factors for disease progression in Chinese subjects: A single-centre retrospective study in Beijing.

Authors:  Zhun Sui; Jiemin Wang; Claudia Cabrera; Jia Wei; Mi Wang; Li Zuo
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  7 in total

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