Literature DB >> 18027967

A facile two-step synthesis of 2-arylbenzofurans based on the selective cross McMurry couplings.

Xin-Fang Duan1, Jing Zeng, Zhan-Bin Zhang, Guo-Fu Zi.   

Abstract

A novel two-step synthesis of 2-arylbenzofurans has been developed. It involves a selective cross McMurry coupling of a salicylaldehyde or substituted salicylaldehyde with an aromatic aldehyde and a sequential oxidative cyclization of the resulting ortho-vinylphenols. Utilizing this synthetic protocol, a variety of 2-arylbenzofurans including cicerfuran have been efficiently synthesized.

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Year:  2007        PMID： 18027967     DOI： 10.1021/jo7019652

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  8 in total

1.  Enhancing the Photostability of Arylvinylenebipyridyl Compounds as Fluorescent Indicators for Intracellular Zinc(II) Ions.

Authors:  Zhao Yuan; Ali H Younes; John R Allen; Michael W Davidson; Lei Zhu
Journal:  J Org Chem       Date:  2015-05-20       Impact factor: 4.354

2.  3,5-Dibromo-2-hydroxy-benzaldehyde.

Authors:  Ying Fan; Wei You; Hui-Fen Qian; Jian-Lan Liu; Wei Huang
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2008-04-04

3.  A Novel Base-Promoted Cyclization: Synthesis of Substituted Benzo[b]furans.

Authors:  Krishna Damera; Bowen Ke; Ke Wang; Chaofeng Dai; Lifang Wang; Binghe Wang
Journal:  RSC Adv       Date:  2012-10-21       Impact factor: 3.361

4.  catena-Poly[copper(II)-bis(μ-2,4-dichloro-6-formyl-phenolato)-κO,O':Cl;κCl:O,O'].

Authors:  Ying Fan; Wei You; Jian-Lan Liu; Hui-Fen Qian; Wei Huang
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2008-07-09

5.  Novel benzofuran derivative DK-1014 attenuates lung inflammation via blocking of MAPK/AP-1 and AKT/mTOR signaling in vitro and in vivo.

Authors:  Xuezhen Xu; Ok-Kyoung Kwon; In-Sik Shin; Jyotirling R Mali; Dipesh S Harmalkar; Yourim Lim; Gilhye Lee; Qili Lu; Sei-Ryang Oh; Kyung-Seop Ahn; Hye-Gwang Jeong; Kyeong Lee
Journal:  Sci Rep       Date:  2019-01-29       Impact factor: 4.379

6.  Facile synthesis of 2-substituted benzo[b]furans and indoles by copper-catalyzed intramolecular cyclization of 2-alkynyl phenols and tosylanilines.

Authors:  Zhouting Rong; Kexin Gao; Lei Zhou; Jianyuan Lin; Guoying Qian
Journal:  RSC Adv       Date:  2019-06-07       Impact factor: 4.036

7.  Nickel catalyzed intramolecular oxidative coupling: synthesis of 3-aryl benzofurans.

Authors:  Sakshi Aggarwal; Dasari Srinivas; Chinnabattigalla Sreenivasulu; Gedu Satyanarayana
Journal:  RSC Adv       Date:  2020-06-10       Impact factor: 4.036

8.  Crossed McMurry Coupling Reactions for Porphycenic Macrocycles: Non-Statistical Selectivity and Rationalisation.

Authors:  Thomas Y Cowie; Lorna Kennedy; Justyna M Żurek; Martin J Paterson; Magnus W P Bebbington
Journal:  European J Org Chem       Date:  2015-04-29
  8 in total

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