| Literature DB >> 18027960 |
Tomoaki Nakamura1, Motoko Oshida, Tomoko Nomura, Atsuo Nakazaki, Susumu Kobayashi.
Abstract
Stereoselective synthesis of a potential intermediate bearing 11-oxabicyclo[6.2.1]undec-3-ene core, a common scaffold of biologically active germacrane-type sesquiterpenes, has been achieved. Synthetic features involve formal 1,3-asymmetric induction, unusual ring-closing metathesis constructing a 10-membered carbocycle system, and unique lactone transposition.Entities:
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Year: 2007 PMID： 18027960 DOI： 10.1021/ol7025119
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005