OBJECT: The shaken baby syndrome (SBS) is an important cause of developmental delay in infants. Epileptic seizures are a common feature of this syndrome. The aim if this study is to analyse the impact of the early and late seizures disorder. MATERIALS AND METHODS: We have retrospectively reviewed the clinical and electrophysiological findings in a series of 404 children hospitalised with SBS. RESULTS: In the acute phase, clinical epileptic seizures of various semiologies were found in 73% of the infants. Only 11% of the children had a normal EEG on admission. A poor outcome was found in 88% of the children in case of persisting EEG anomalies despite anti-epileptic treatment with 48% mortality in these patients. The development of refractory epilepsy was also associated with a poor outcome in this series. In fact 96% of the children with seizure recurrence had behavioural problems. CONCLUSIONS: The early recognition and subsequent management of these seizures is vital to prevent further neurological injury. Delayed or recurrent epileptic seizures may occur with a different semiology to the seizures in the acute phase and are also associated with a poor prognosis.
OBJECT: The shaken baby syndrome (SBS) is an important cause of developmental delay in infants. Epilepticseizures are a common feature of this syndrome. The aim if this study is to analyse the impact of the early and late seizures disorder. MATERIALS AND METHODS: We have retrospectively reviewed the clinical and electrophysiological findings in a series of 404 children hospitalised with SBS. RESULTS: In the acute phase, clinical epilepticseizures of various semiologies were found in 73% of the infants. Only 11% of the children had a normal EEG on admission. A poor outcome was found in 88% of the children in case of persisting EEG anomalies despite anti-epileptic treatment with 48% mortality in these patients. The development of refractory epilepsy was also associated with a poor outcome in this series. In fact 96% of the children with seizure recurrence had behavioural problems. CONCLUSIONS: The early recognition and subsequent management of these seizures is vital to prevent further neurological injury. Delayed or recurrent epilepticseizures may occur with a different semiology to the seizures in the acute phase and are also associated with a poor prognosis.
Authors: Joshua L Goldstein; Daniel Leonhardt; Natalie Kmytyuk; Francine Kim; Deli Wang; Mark S Wainwright Journal: Neurocrit Care Date: 2011-08 Impact factor: 3.210
Authors: Jakob Matschke; Bernd Herrmann; Jan Sperhake; Friederike Körber; Thomas Bajanowski; Markus Glatzel Journal: Dtsch Arztebl Int Date: 2009-03-27 Impact factor: 5.594
Authors: Daphne M Hasbani; Alexis A Topjian; Stuart H Friess; Todd J Kilbaugh; Robert A Berg; Cindy W Christian; Dennis J Dlugos; Jimmy Huh; Nicholas S Abend Journal: Pediatr Crit Care Med Date: 2013-09 Impact factor: 3.624