Literature DB >> 180269

Relationship between bone uptake of 99mTc-pyrophosphate and hydroxyproline in blood and urine.

T Wiegmann, J Kirsh, L Rosenthall, M Kaye.   

Abstract

In a group of hospital patients with various diseases, the urinary hydroxyproline-to-creatinine ratio showed a significant correlation (r = 0.63; p less than 0.001) with the 5-hr bone-to-soft-tissue ratio for 99mTc-pyrophosphate uptake. In patients on chronic hemodialysis, a similar correlation was found between the 5-hr bone-to-soft-tissue ratio and hydroxyproline levels in plasma and serum. The findings suggest that 99mTc-pyrophosphate binding by bone is related to collagen metabolism.

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Year:  1976        PMID: 180269

Source DB:  PubMed          Journal:  J Nucl Med        ISSN: 0161-5505            Impact factor:   10.057


  3 in total

1.  A critical assessment of bone scan quantitation (bone to soft tissue ratios) in the diagnosis of metabolic bone disease.

Authors:  I Fogelman; R G Bessent; D Gordon
Journal:  Eur J Nucl Med       Date:  1981-03

2.  Whole body and regional retention of 99mTc-labeled pyrophosphate at 24 hours: physiological basis of the method for assessing the metabolism of bone in disease.

Authors:  P Martin; A Schoutens; D Manicourt; P Bergmann; M Fuss; M Verbanck
Journal:  Calcif Tissue Int       Date:  1983       Impact factor: 4.333

3.  Deconvolution analysis of 99mTc-methylene diphosphonate kinetics in metabolic bone disease.

Authors:  J Knop; E Kröger; P Stritzke; C Schneider; H P Kruse
Journal:  Eur J Nucl Med       Date:  1981-02
  3 in total

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