Literature DB >> 180258

Metronidazole neuropathy.

A Coxon, C A Pallis.   

Abstract

Two patients are described who developed sensory neuropathy after the ingestion of 30.6 and 114 g metronidazole respectively. The drug, widely used in gastroenterological and gynaecological practice, has not hitherto been considered neurotoxic. The implications are stressed in relation to the differential diagnosis of patients with gastroenterological disorders who develop peripheral neuropathy.

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Year:  1976        PMID： 180258      PMCID： PMC492292          DOI： 10.1136/jnnp.39.4.403

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN： 0022-3050            Impact factor:   10.154


  8 in total

1.  The range of conduction velocity in normal motor nerve fibers to the small muscles of the hand and foot.

Authors:  P K THOMAS; T A SEARS; R W GILLIATT
Journal:  J Neurol Neurosurg Psychiatry       Date:  1959-08       Impact factor: 10.154

2.  Sensory nerve action potentials in patients with peripheral nerve lesions.

Authors:  R W GILLIATT; T A SEARS
Journal:  J Neurol Neurosurg Psychiatry       Date:  1958-05       Impact factor: 10.154

3.  Activity of metronidazole against experimental tetanus and gas gangrene.

Authors:  W A Freeman; J A McFadzean; J P Whelan
Journal:  J Appl Bacteriol       Date:  1968-12

4.  Endocrine ophthalmopathy.

Authors:  I D Ramsay
Journal:  Br Med J       Date:  1968-12-14

5.  Letter: "High-dose" metronidazole: a preliminary pharmacological study prior to its investigational use in clinical radiotherapy trials.

Authors:  R C Urtasun; J Sturmwind; H Rabin; P R Band; J D Chapman
Journal:  Br J Radiol       Date:  1974-05       Impact factor: 3.039

6.  Immunoglobulin deficiency and regional enteritis.

Authors:  J Söltoft; L Petersen; P Kruse
Journal:  Scand J Gastroenterol       Date:  1972       Impact factor: 2.423

Review 7.  Subacute myelo-optic neuropathy and clioquinol. An epidemiological case-history for diagnosis.

Authors:  T W Meade
Journal:  Br J Prev Soc Med       Date:  1975-09

8.  Metronidazole for Crohn's disease.

Authors:  B Ursing; C Kamme
Journal:  Lancet       Date:  1975-04-05       Impact factor: 79.321
  8 in total
  14 in total

1.  Metronidazole neuropathy.

Authors:  W G Bradley; I J Karlsson; C G Rassol
Journal:  Br Med J       Date:  1977-09-03

2.  Further clinical experiences of a phase I study with the hypoxic cell radiosensitizer misonidazole.

Authors:  H D Kogelnik; J H Meyer; K Jentzsch; T Szepesi; K H Kärcher; E Maida; B Mamoli; P Wessely; F Zaunbauer
Journal:  Br J Cancer Suppl       Date:  1978-06

Review 3.  HIV-associated neuropathic pain: epidemiology, pathophysiology and management.

Authors:  Susama Verma; Lydia Estanislao; David Simpson
Journal:  CNS Drugs       Date:  2005       Impact factor: 5.749

4.  Giardiasis and peripheral neuropathy.

Authors:  M L Bassett; G Danta; T A Cook
Journal:  Br Med J       Date:  1978-07-01

5.  Metronidazole neuropathy.

Authors: 
Journal:  Br Med J       Date:  1977-09-24

6.  Drug-induced peripheral neuropathies.

Authors:  Z Argov; F L Mastaglia
Journal:  Br Med J       Date:  1979-03-10

Review 7.  Clinical pharmacokinetics of metronidazole.

Authors:  E D Ralph
Journal:  Clin Pharmacokinet       Date:  1983 Jan-Feb       Impact factor: 6.447

Review 8.  Environmental effects on the central nervous system.

Authors:  G W Paulson
Journal:  Environ Health Perspect       Date:  1977-10       Impact factor: 9.031

9.  Peripheral neuropathy complicating pancreatitis and major pancreatic surgery.

Authors:  M L Gross; C J Fowler; R Ho; R C Russell; M J Harrison
Journal:  J Neurol Neurosurg Psychiatry       Date:  1988-10       Impact factor: 10.154

10.  The effect of the radiosensitizer misonidazole on motor nerve conduction velocity in the mouse.

Authors:  D G Hirst; B Vojnovic; I J Stratford; E L Travis
Journal:  Br J Cancer Suppl       Date:  1978-06
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