Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 cAMP response element binding protein (CREB) overexpression CREB has been described as critical for leukemia progression.

Literature DB >> 18024382

cAMP response element binding protein (CREB) overexpression CREB has been described as critical for leukemia progression.

Martina Pigazzi, Emanuela Ricotti, Giuseppe Germano, Diego Faggian, Maurizio Aricò, Giuseppe Basso.

Abstract

CREB has been described as critical for leukemia progress. We investigated CREB expression in ALL and AML pediatric patients. CREB protein was significantly high (p<0.001) at diagnosis but not during remission. This study underlines the role of CREB in leukemia and suggests new insights into the transformation process.

Entities: Disease Gene Species

Mesh：

Substances：

Year: 2007 PMID： 18024382 DOI： 10.3324/haematol.11122

Source DB: PubMed Journal: Haematologica ISSN： 0390-6078 Impact factor: 9.941

Keyword Cloud
Cited

21 in total

1. Targeting CREB for cancer therapy: friend or foe.

Authors: Xiangshu Xiao; Bingbing X Li; Bryan Mitton; Alan Ikeda; Kathleen M Sakamoto
Journal: Curr Cancer Drug Targets Date: 2010-06 Impact factor: 3.428

2. p-CREB expression in human meningiomas: correlation with angiogenesis and recurrence risk.

Authors: Valeria Barresi; Giovanni Branca; Maria Caffo; Giovanni Tuccari
Journal: J Neurooncol Date: 2015-01-07 Impact factor: 4.130

3. Sox4 cooperates with CREB in myeloid transformation.

Authors: Salemiz Sandoval; Christina Kraus; Er-Chieh Cho; Michelle Cho; Juraj Bies; Elena Manara; Benedetta Accordi; Elliot M Landaw; Linda Wolff; Martina Pigazzi; Kathleen M Sakamoto
Journal: Blood Date: 2012-05-24 Impact factor: 22.113

4. MicroRNA-200b targets CREB1 and suppresses cell growth in human malignant glioma.

Authors: Biao Peng; Su Hu; Qinming Jun; Dongdong Luo; Xun Zhang; Hailin Zhao; Dan Li
Journal: Mol Cell Biochem Date: 2013-03-30 Impact factor: 3.396

5. CREB in the pathophysiology of cancer: implications for targeting transcription factors for cancer therapy.

Authors: Kathleen M Sakamoto; David A Frank
Journal: Clin Cancer Res Date: 2009-04-07 Impact factor: 12.531

6. Activated cAMP response element binding protein is overexpressed in human mesotheliomas and inhibits apoptosis.

Authors: Arti Shukla; Marcus W Bosenberg; Maximilian B MacPherson; Kelly J Butnor; Nicholas H Heintz; Harvey I Pass; Michele Carbone; Joseph R Testa; Brooke T Mossman
Journal: Am J Pathol Date: 2009-10-08 Impact factor: 4.307

7. MicroRNA-34b promoter hypermethylation induces CREB overexpression and contributes to myeloid transformation.

Authors: Martina Pigazzi; Elena Manara; Silvia Bresolin; Claudia Tregnago; Alessandra Beghin; Emma Baron; Emanuela Giarin; Er-Chieh Cho; Riccardo Masetti; Dinesh S Rao; Kathleen M Sakamoto; Giuseppe Basso
Journal: Haematologica Date: 2012-10-25 Impact factor: 9.941