Literature DB >> 18024380

Clinical features and outcomes of 134 Brazilians with acute promyelocytic leukemia who received ATRA and anthracyclines.

Rafael Henriques Jácomo, Raul Antonio Morais Melo, Fernanda Ribeiro Souto, Ederson Roberto de Mattos, Claudia Teresa de Oliveira, Evandro M Fagundes, Henrique Neves da Silva Bittencourt, Rosane Isabel Bittencourt, Teresa Cristina Bortolheiro, Eduardo J A Paton, Rodrigo Bendlin, Sebastião Ismael, Maria de Lourdes Chauffaille, Dirceu Silva, Katia Borgia B Pagnano, Raul Ribeiro, Eduardo M Rego.   

Abstract

We report an increased incidence of high relapse risk features in 157 APL Brazilian patients. Out of 134 patients treated with ATRA and anthracyclines, only 91 (67.9%) achieved remission because 43 (32%) died during induction. The death rate during consolidation was 10.5%. Bleeding complications were the most frequent cause of failure (21.6%).

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Year:  2007        PMID： 18024380     DOI： 10.3324/haematol.10874

Source DB:  PubMed          Journal:  Haematologica        ISSN： 0390-6078            Impact factor:   9.941


  39 in total

1.  Prompt all-trans retinoic acid administration and early death in acute promyelocytic leukemia: what does the evidence say?

Authors:  A Rashidi; S I Fisher
Journal:  Leukemia       Date:  2014-09-17       Impact factor: 11.528

2.  Combining gene mutation with gene expression analysis improves outcome prediction in acute promyelocytic leukemia.

Authors:  Antonio R Lucena-Araujo; Juan L Coelho-Silva; Diego A Pereira-Martins; Douglas R Silveira; Luisa C Koury; Raul A M Melo; Rosane Bittencourt; Katia Pagnano; Ricardo Pasquini; Elenaide C Nunes; Evandro M Fagundes; Ana B Gloria; Fábio Kerbauy; Maria de Lourdes Chauffaille; Israel Bendit; Vanderson Rocha; Armand Keating; Martin S Tallman; Raul C Ribeiro; Richard Dillon; Arnold Ganser; Bob Löwenberg; P J M Valk; Francesco Lo-Coco; Miguel A Sanz; Nancy Berliner; Eduardo M Rego
Journal:  Blood       Date:  2019-07-10       Impact factor: 22.113

3.  Acute promyelocytic leukemia associated with the PLZF-RARA fusion gene: two additional cases with clinical and laboratorial peculiar presentations.

Authors:  Sandra S Rohr; Luís Arthur Flores Pelloso; Aline Borgo; Livia Chiosini De Nadai; Mihoko Yamamoto; Eduardo M Rego; Maria de Lourdes L F Chauffaille
Journal:  Med Oncol       Date:  2011-12-29       Impact factor: 3.064

4.  Clinical impact of BAALC expression in high-risk acute promyelocytic leukemia.

Authors:  Antonio R Lucena-Araujo; Diego A Pereira-Martins; Luisa C Koury; Pedro L Franca-Neto; Juan L Coelho-Silva; Virginia M de Deus Wagatsuma; Raul A M Melo; Rosane Bittencourt; Katia Pagnano; Ricardo Pasquini; Carlos S Chiattone; Evandro M Fagundes; Maria de Lourdes Chauffaille; Stanley L Schrier; Martin S Tallman; Raul C Ribeiro; David Grimwade; Arnold Ganser; Bob Löwenberg; Francesco Lo-Coco; Miguel A Sanz; Nancy Berliner; Eduardo M Rego
Journal:  Blood Adv       Date:  2017-09-15

Review 5.  Pathogenesis of disseminated intravascular coagulation in patients with acute promyelocytic leukemia, and its treatment using recombinant human soluble thrombomodulin.

Authors:  Takayuki Ikezoe
Journal:  Int J Hematol       Date:  2013-11-12       Impact factor: 2.490

6.  The results of the International Consortium on Acute Promyelocytic Leukemia: a 'proof of concept' of networking as a strategy to improve the outcome of treatment of hematological malignancies in developing countries.

Authors:  Eduardo Magalhães Rego
Journal:  Rev Bras Hematol Hemoter       Date:  2013

7.  Treatment outcome of acute promyelocytic leukemia with modified aida protocol.

Authors:  Kátia B Barbosa Pagnano; Gustavo de Carvalho Duarte; Irene Lorand-Metze; Márcia Torresan Delamain; Eliana Cristina Miranda; Cármino Antonio De Souza
Journal:  Adv Hematol       Date:  2010-05-16

8.  Outcome of acute myeloid leukemia patients with hyperleukocytosis in Brazil.

Authors:  L C O Oliveira; L G M Romano; B P A Prado-Junior; D T Covas; E M Rego; G C De Santis
Journal:  Med Oncol       Date:  2009-11-25       Impact factor: 3.064

9.  International Society of Thrombosis and Hemostasis Scoring System for disseminated intravascular coagulation ≥ 6: a new predictor of hemorrhagic early death in acute promyelocytic leukemia.

Authors:  Mirjana Mitrovic; Nada Suvajdzic; Andrija Bogdanovic; Nada Kraguljac Kurtovic; Aleksandra Sretenovic; Ivo Elezovic; Dragica Tomin
Journal:  Med Oncol       Date:  2013-01-31       Impact factor: 3.064

10.  Genital ulcer development in patients with acute promyelocytic leukaemia treated with all-trans retinoic Acid: a case series.

Authors:  Mohammed Al Huneini; Fauzia Wasim; Khalil Al Farsi; Murtadha Al-Khabori; Salam Al Kindi
Journal:  Oman Med J       Date:  2013-05
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