| Literature DB >> 18024118 |
Mathieu F Cellier1, Pascal Courville, Carole Campion.
Abstract
Natural resistance-associated macrophage proteins (Nramp) are multispecific symporters facilitating proton-dependent import of divalent metals. Nramp1 restricts microbial access to essential micro-nutrients such as iron and manganese within professional phagosomes. Increased understanding of Nramp1 roles in human phagocytes will be useful for future therapeutic approaches against selected infectious and immune diseases.Entities:
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Year: 2007 PMID： 18024118 DOI： 10.1016/j.micinf.2007.09.006
Source DB: PubMed Journal: Microbes Infect ISSN： 1286-4579 Impact factor: 2.700